[HTML][HTML] Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain

Y Yao, A Yonezawa, H Yoshimatsu, S Masuda… - The Journal of …, 2010 - Elsevier
We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1

A Yonezawa, S Masuda… - American Journal of …, 2008 - journals.physiology.org
Absorption of riboflavin is mediated by transporter (s). However, a mammalian riboflavin
transporter has yet to be identified. In the present study, the novel human and rat riboflavin …

Identification and functional characterization of rat riboflavin transporter 2

S Yamamoto, K Inoue, K Ohta, R Fukatsu… - Journal of …, 2009 - academic.oup.com
We have newly identified rat riboflavin transporter 2 (rRFT2) and its human orthologue
(hRFT2), and carried out detailed functional characterization of rRFT2. The mRNA of rRFT2 …

[HTML][HTML] Functional characteristics of the human ortholog of riboflavin transporter 2 and riboflavin-responsive expression of its rat ortholog in the small intestine indicate …

M Fujimura, S Yamamoto, T Murata, T Yasujima… - The Journal of …, 2010 - Elsevier
Riboflavin transporter (RFT) 2 has recently been identified as a transporter that may be,
mainly based on the functional characteristics of its rat ortholog (rRFT2), involved in the …

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells

VS Subramanian, L Rapp… - American Journal of …, 2011 - journals.physiology.org
The water-soluble vitamin B2 (riboflavin, RF) is an essential micronutrient for normal cell
function and survival. Recent studies have identified a role for the human riboflavin …

[HTML][HTML] Differential expression of human riboflavin transporters-1,-2, and-3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake

VS Subramanian, SB Subramanya, L Rapp… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Transport of riboflavin (RF) across both the brush border membrane (BBM) and basolateral
membrane (BLM) of the polarized enterocyte occurs via specific carrier-mediated …

Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52

A Yonezawa, K Inui - Molecular aspects of medicine, 2013 - Elsevier
Riboflavin, a water-soluble vitamin also known as vitamin B2, is essential for normal cellular
functions. Riboflavin transporters play important roles in its homeostasis. Recently, three …

Riboflavin transporter is finally identified

Y Moriyama - The Journal of Biochemistry, 2011 - academic.oup.com
Riboflavin or vitamin B2 is one of the constituents of energy drinks. Although this compound
is known to be absorbed in the intestine and that it circulates throughout the body and is …

[HTML][HTML] Evaluation of riboflavin transporters as targets for drug delivery and theranostics

L Bartmann, D Schumacher, S Von Stillfried… - Frontiers in …, 2019 - frontiersin.org
The retention and cellular internalization of drug delivery systems and theranostics for
cancer therapy can be improved by targeting molecules. Since an increased uptake of …

Disorders of riboflavin metabolism

S Balasubramaniam, J Christodoulou… - Journal of inherited …, 2019 - Wiley Online Library
Abstract Riboflavin (vitamin B2), a water‐soluble vitamin, is an essential nutrient in higher
organisms as it is not endogenously synthesised, with requirements being met principally by …