Free radicals, metals and antioxidants in oxidative stress-induced cancer

M Valko, CJB Rhodes, J Moncol, MM Izakovic… - Chemico-biological …, 2006 - Elsevier
Oxygen-free radicals, more generally known as reactive oxygen species (ROS) along with
reactive nitrogen species (RNS) are well recognised for playing a dual role as both …

The involvement of the oxidative stress status in cancer pathology: a double view on the role of the antioxidants

KF Zahra, R Lefter, A Ali, EC Abdellah… - Oxidative Medicine …, 2021 - Wiley Online Library
Oxygen‐free radicals, reactive oxygen species (ROS) or reactive nitrogen species (RNS),
are known by their “double‐sided” nature in biological systems. The beneficial effects of …

Role of oxidative stress and DNA damage in human carcinogenesis

TB Kryston, AB Georgiev, P Pissis… - … Molecular Mechanisms of …, 2011 - Elsevier
Cells in tissues and organs are continuously subjected to oxidative stress and free radicals
on a daily basis. This free radical attack has exogenous or endogenous (intracellular) origin …

Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?

R Olinski, D Gackowski, R Rozalski, M Foksinski… - Mutation Research …, 2003 - Elsevier
A wide variety of oxidative DNA lesions are present in living cells. One of the best known
lesions of this type is 8-oxoguanine (8-oxoGua) which has been shown to have mutagenic …

Oxidative stress in cancer cell metabolism

S Arfin, NK Jha, SK Jha, KK Kesari, J Ruokolainen… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are important in regulating normal cellular processes
whereas deregulated ROS leads to the development of a diseased state in humans …

Free radicals and antioxidants in normal physiological functions and human disease

M Valko, D Leibfritz, J Moncol, MTD Cronin… - The international journal …, 2007 - Elsevier
Reactive oxygen species (ROS) and reactive nitrogen species (RNS, eg nitric oxide, NO) are
well recognised for playing a dual role as both deleterious and beneficial species. ROS and …

Reactive oxygen species and cancer paradox: to promote or to suppress?

S Galadari, A Rahman, S Pallichankandy… - Free Radical Biology …, 2017 - Elsevier
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

The differential role of reactive oxygen species in early and late stages of cancer

M Assi - … Journal of Physiology-Regulatory, Integrative and …, 2017 - journals.physiology.org
The large doses of vitamins C and E and β-carotene used to reduce reactive oxygen species
(ROS) production and oxidative damages in cancerous tissue have produced disappointing …

Oxidative stress and cancer: advances and challenges

S Prasad, SC Gupta, MK Pandey… - Oxidative medicine and …, 2016 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) constantly generated inside the body are required to drive
regulatory pathways and are also a cause for several pathological conditions including …

Advances in carcinogenic metal toxicity and potential molecular markers

P Koedrith, YR Seo - International journal of molecular sciences, 2011 - mdpi.com
Metal compounds such as arsenic, cadmium, chromium, cobalt, lead, mercury, and nickel
are classified as carcinogens affecting human health through occupational and …