This study aimed to optimize and evaluate a thermoresponsive ophthalmic in situ gel
containing curcumin-loaded albumin nanoparticles (Cur-BSA-NPs-Gel). Albumin …

Context: The nanogel combining cationic nanostructured lipid carriers (CNLC) and
thermosensitive gelling agent could enhance preocular retention and ocular permeation …

Curcumin (Cur) is a naturally hydrophobic polyphenol with potential pharmacological
properties. However, the poor aqueous solubility and low bioavailability of curcumin limits its …

Intraocular inflammation seriously impairs vision, and the effectiveness of intraocular drug
delivery is hampered by various physiological barriers, such as the corneal barrier. In this …

The search for an ocular drug delivery system that could provide long-acting effects without
a detriment to the anatomy and physiology of the eye remains a challenge. Polyphenolic …

Triblock poloxamer copolymer (PM) has been extensively utilized to deliver various
ophthalmic pharmaceutical compounds. The aim of efficient ophthalmic drug delivery …

Curcumin, a natural polyphenol compound, has been widely reported for diverse
pharmacological effects and already been investigated for eye diseases. However, the water …

This work was conducted to optimize and evaluate Pluronic F127-based thermoresponsive
diclofenac sodium ophthalmic in situ gels (DS in situ gel). They were prepared by cold …

The contemporary research implicates the formulation and evaluation of a thermosensitive
in situ nano gelling method to improve solubility and ocular residence time of flurbiprofen …

A novel nano in situ gel forming system of 5-Fluorouracil (5-FU) was investigated for its
potential use for conjunctival/corneal squamous cell carcinoma (CCSC). The study was …