Precision medicine in airway diseases: moving to clinical practice

A Agustí, M Bafadhel, R Beasley, EH Bel… - European …, 2017 - Eur Respiratory Soc
On February 21, 2017, a European Respiratory Society research seminar held in Barcelona
discussed how to best apply precision medicine to chronic airway diseases such as asthma …

Treatable traits: toward precision medicine of chronic airway diseases

A Agusti, E Bel, M Thomas… - European …, 2016 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic
airway diseases that have a high personal and social impact. They likely represent a …

What is precision medicine?

IR König, O Fuchs, G Hansen… - European respiratory …, 2017 - Eur Respiratory Soc
The term “precision medicine” has become very popular over recent years, fuelled by
scientific as well as political perspectives. Despite its popularity, its exact meaning, and how …

Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms?

LEGW Vanfleteren, JWH Kocks, IS Stone… - Thorax, 2014 - thorax.bmj.com
In the majority of cases, asthma and chronic obstructive pulmonary disease (COPD) are two
clearly distinct disease entities. However, in some patients there may be significant overlap …

Personalised medicine in asthma: time for action: Number 1 in the Series “Personalised medicine in respiratory diseases” Edited by Renaud Louis and Nicolas Roche

KF Chung - European Respiratory Review, 2017 - Eur Respiratory Soc
Asthma is a heterogeneous disease comprising several phenotypes driven by different
pathways. To define these phenotypes or endotypes (phenotypes defined by mechanisms) …

Introduction to precision medicine in COPD

JM Leung, M Obeidat, M Sadatsafavi… - European Respiratory …, 2019 - Eur Respiratory Soc
Although there has been tremendous growth in our understanding of chronic obstructive
pulmonary disease (COPD) and its pathophysiology over the past few decades, the pace of …

Precision medicine in COPD: where are we and where do we need to go?

VK Sidhaye, K Nishida… - European Respiratory …, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) was the fourth leading cause of death
worldwide in 2015. Current treatments for patients ease discomfort and help decrease …

From treatable traits to GETomics in airway disease: moving towards clinical practice

A Papi, R Faner, I Pavord, F Baraldi… - European …, 2024 - Eur Respiratory Soc
The treatable traits approach represents a strategy for patient management. It is based on
the identification of characteristics susceptible to treatments or predictive of treatment …

Treatable traits in airway disease: from theory to practice

A Agusti, PG Gibson, VM McDonald - The Journal of Allergy and Clinical …, 2023 - Elsevier
Chronic airway diseases such as asthma and chronic obstructive pulmonary disease are
prevalent and complex conditions that often coexist in the same patient. To address this …

Precision medicine in asthma: linking phenotypes to targeted treatments

KF Chung - Current opinion in pulmonary medicine, 2018 - journals.lww.com
Unbiased definition of phenotypes or endotypes (which are phenotypes defined by
mechanisms) is an important step towards the use of precision medicine in asthma …