Functional and morphological evidence for a ventricular conduction system in zebrafish and Xenopus hearts

D Sedmera, M Reckova, A DeAlmeida… - American Journal …, 2003 - journals.physiology.org
Zebrafish and Xenopus have become popular model organisms for studying vertebrate
development of many organ systems, including the heart. However, it is not clear whether …

The zebrafish heart as a model of mammalian cardiac function

CE Genge, E Lin, L Lee, XY Sheng, K Rayani… - Reviews of Physiology …, 2016 - Springer
Zebrafish (Danio rerio) are widely used as vertebrate model in developmental genetics and
functional genomics as well as in cardiac structure-function studies. The zebrafish heart has …

Cardiac morphology and blood pressure in the adult zebrafish

N Hu, HJ Yost, EB Clark - … Record: An Official Publication of the …, 2001 - Wiley Online Library
Zebrafish has become a popular model for the study of cardiovascular development. We
performed morphologic analysis on 3 months postfertilization zebrafish hearts (n≥ 20) with …

Zebrafish heart as a model for human cardiac electrophysiology

M Vornanen, M Hassinen - Channels, 2016 - Taylor & Francis
The zebrafish (Danio rerio) has become a popular model for human cardiac diseases and
pharmacology including cardiac arrhythmias and its electrophysiological basis. Notably, the …

Adult zebrafish heart as a model for human heart? An electrophysiological study

P Nemtsas, E Wettwer, T Christ, G Weidinger… - Journal of molecular and …, 2010 - Elsevier
The zebrafish has recently emerged as an excellent model for studies of heart development
and regeneration. The physiology of the zebrafish heart has been suggested to resemble …

Ionic basis of cardiac electrophysiology in zebrafish compared to human hearts

U Ravens - Progress in biophysics and molecular biology, 2018 - Elsevier
Zebrafish heart has evolved as an intensely studied model for cardiac development,
physiology and pathophysiology. A particular advantage is its morphological and functional …

Zebrafish heart as a model to study the integrative autonomic control of pacemaker function

MR Stoyek, TA Quinn, RP Croll… - American Journal of …, 2016 - journals.physiology.org
The cardiac pacemaker sets the heart's primary rate, with pacemaker discharge controlled
by the autonomic nervous system through intracardiac ganglia. A fundamental issue in …

Developmental transitions in electrical activation patterns in chick embryonic heart

D Sedmera, M Reckova, MR Bigelow… - … Record Part A …, 2004 - Wiley Online Library
The specialized conduction tissue network mediates coordinated propagation of electrical
activity through the adult vertebrate heart. Following activation of the atria, the activation …

Changing activation sequence in the embryonic chick heart: implications for the development of the His-Purkinje system

ET Chuck, DM Freeman, M Watanabe… - Circulation …, 1997 - Am Heart Assoc
In the mature heart, impulse propagation through the His-Purkinje system (HPS) is required
for efficient ventricular contraction in an apex-to-base direction. However, the embryonic …

Structure and function of the developing zebrafish heart

N Hu, D Sedmera, HJ Yost… - The Anatomical Record …, 2000 - Wiley Online Library
The combination of optical clarity and large scale of mutants makes the zebrafish vital for
developmental biologists. However, there is no comprehensive reference of morphology …