Extracellular vesicles (EVs), produced during viral infections, are of emerging interest in
understanding infectious processes and host–pathogen interactions. EVs and exosomes in …

The arthropod-borne flaviviruses are important human pathogens, and a deeper
understanding of the virus–host cell interaction is required to identify cellular targets that can …

Abstract Background Extracellular vesicles (EVs) are small membrane vesicles secreted by
the cells that mediate intercellular transfer of molecules and contribute to transduction of …

Mosquito‐borne flaviviruses including Zika virus (ZIKV) represent a public health problem in
some parts of the world. Although ZIKV infection is predominantly asymptomatic or …

Dengue virus NS1 is a glycoprotein of 46–50 kDa that is conserved among flaviviruses,
associates as a dimer to cell membranes and is secreted as a hexamer to the extracellular …

The flavivirus nonstructural protein NS1 is expressed as three discrete species in infected
mammalian cells: an intracellular, membrane-associated form essential for viral replication …

Zika fever is a reemerging arthropod-borne viral disease; however, Zika virus (ZIKV) can be
transmitted by other, non-vector means. Severe Zika fever is characterized by neurological …

Most cells can release extracellular vesicles (EVs), membrane vesicles containing various
proteins, nucleic acids, enzymes, and signaling molecules. The exchange of EVs between …

The mosquito-borne viral disease dengue is a global public health problem causing a wide
spectrum of clinical manifestations ranging from mild dengue fever to severe dengue with …

Although flaviviruses co-opt the function of the host endoplasmic reticulum (ER) membrane
protein complex (EMC) during infection, a mechanistic explanation for this observation …