The consumption of synthetic cannabinoids during adolescence is reported to be a risk
factor for the appearance of psychiatric disorders later in life. JWH-018 was identified as one …

Rationale The use of synthetic cannabinoid receptor agonists (SCRAs) is growing among
adolescents, posing major medical and psychiatric risks. JWH-018 represents the reference …

JWH-073 is a synthetic cannabinoid (SCB) that is illegally marketed within an “herbal blend”,
causing psychoactive effects more intense than those produced by Cannabis. Users report …

Abstract Background and Purpose Psychotic disorders have been reported in long‐term
users of synthetic cannabinoids. This study aims at investigating the long‐lasting effects of …

The active components associated with the bio-designer drugs known variously as “Spice”
or “K2” have rapidly gained in popularity among recreational users, forcing the United States …

Naphthalen-1-yl-(1-pentylindol-3-yl) methanone (JWH-018) is a synthetic compound found
in psychoactive “spice” products that activates cannabinoid receptors. Preclinical evidence …

Background and Purpose Spice/K2 herbal mixtures, containing synthetic cannabinoids such
as JWH‐018, have been marketed as marijuana surrogates since 2004. JWH‐018 has …

Marijuana, a psychoactive drug that activates cannabinoid-1 (CB1) receptors in the brain, is
the most prevalently abused illicit drug among American adolescents and young adults …

Regular use of marijuana during adolescence enhances the risk of long‐lasting
neurobiological changes in adulthood. The present study was aimed at assessing the effect …

Synthetic cannabinoid compounds are marketed as “legal” marijuana substitutes, even
though little is known about their behavioral effects in relation to their pharmacokinetic …