[HTML][HTML] Cross-talk between IFN-γ and TWEAK through miR-149 amplifies skin inflammation in psoriasis

A Srivastava, L Luo, W Lohcharoenkal… - Journal of Allergy and …, 2021 - Elsevier
Background Psoriasis is a chronic inflammatory skin disease with disturbed interplay
between immune cells and keratinocytes. A strong IFN-γ signature is characteristic for …

Downregulated miR‐187 contributes to the keratinocytes hyperproliferation in psoriasis

L Tang, S He, Y Zhu, B Feng, Z Su, B Liu… - Journal of Cellular …, 2019 - Wiley Online Library
Psoriasis is a common chronic skin disease characterized by epidermal hyperplasia and
inflammation. However, the pathogenesis of psoriasis is multifactorial and is not fully …

Involvement of miR-214-3p/FOXM1 axis during the progression of psoriasis

J Zhao, F Wang, Q Tian, J Dong, L Chen, R Hu - Inflammation, 2022 - Springer
Psoriasis is a common, chronic, and relapsing skin disease characterized by
hyperproliferation of keratinocytes and apoptosis delay. However, the molecular …

MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40

N Xu, F Meisgen, LM Butler, G Han… - The Journal of …, 2013 - journals.aai.org
Psoriasis is characterized by a specific microRNA expression profile, distinct from that of
healthy skin. MiR-31 is one of the most highly overexpressed microRNAs in psoriasis skin; …

MicroRNA-124 alleviates chronic skin inflammation in atopic eczema via suppressing innate immune responses in keratinocytes

Z Yang, B Zeng, C Wang, H Wang, P Huang, Y Pan - Cellular Immunology, 2017 - Elsevier
Chronic skin inflammation in atopic eczema is associated with elevated expression of
proinflammatory genes and activation of innate immune responses in keratinocytes …

[PDF][PDF] Down-regulation of miR-155 after treatment with narrow-band UVB and methotrexate associates with apoptosis of keratinocytes in psoriasis

W Soonthornchai, P Tangtanatakul… - Asian Pacific Journal …, 2021 - apjai-journal.org
Background: Psoriasis is a chronic inflammatory skin disease arising from a complex
interaction between genetics, epigenetics, the host's immune system and the environment …

IL6R is a target of miR‐197 in human keratinocytes

M Masalha, D Gur‐Wahnon… - Experimental …, 2021 - Wiley Online Library
Psoriasis is a chronic inflammatory disorder with cutaneous and systemic manifestations
and substantial negative effects on patients' quality of life. MicroRNAs (miRNAs) are post …

miR‐378a regulates keratinocyte responsiveness to interleukin‐17A in psoriasis

P Xia, L Pasquali, C Gao, A Srivastava… - British Journal of …, 2022 - academic.oup.com
Background Psoriasis is an immune‐mediated inflammatory skin disease, in which an
interplay between infiltrating immune cells and keratinocytes sustains chronic skin …

TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy

RK Gupta, DT Gracias, DS Figueroa, H Miki… - Science …, 2021 - science.org
TNF and IL-17 are two cytokines that drive dysregulated keratinocyte activity, and their
targeting is highly efficacious in patients with psoriasis, but whether these molecules act with …

[HTML][HTML] miR-4516, a microRNA downregulated in psoriasis inhibits keratinocyte motility by targeting fibronectin/integrin α9 signaling

S Chowdhari, K Sardana, N Saini - … Acta (BBA)-Molecular Basis of Disease, 2017 - Elsevier
Psoriasis is recognized as a T cell mediated inflammatory hyperproliferative skin disorder.
Several microRNAs (miRNAs) have been implicated in the pathogenesis of psoriasis …