Switchable fluorophores for single-molecule localization microscopy

H Li, JC Vaughan - Chemical reviews, 2018 - ACS Publications
The past decade has witnessed an explosion in the use of super-resolution fluorescence
microscopy methods in biology and other fields. Single-molecule localization microscopy …

Chemistry of photosensitive fluorophores for single-molecule localization microscopy

FM Jradi, LD Lavis - ACS Chemical Biology, 2019 - ACS Publications
Development of single-molecule localization microscopy (SMLM) has sparked a revolution
in biological imaging, allowing “super-resolution” fluorescence microscopy below the …

Single-molecule localization microscopy–near-molecular spatial resolution in light microscopy with photoswitchable fluorophores

A Fürstenberg, M Heilemann - Physical Chemistry Chemical Physics, 2013 - pubs.rsc.org
Fluorescence imaging beyond the diffraction limit has grown into a method of choice to
elucidate questions related to biological structure and organisation. Among super-resolution …

Photochemical mechanisms of fluorophores employed in single‐molecule localization microscopy

K Kikuchi, LD Adair, J Lin, EJ New… - Angewandte Chemie, 2023 - Wiley Online Library
Decoding cellular processes requires visualization of the spatial distribution and dynamic
interactions of biomolecules. It is therefore not surprising that innovations in imaging …

Single-molecule localization microscopy in eukaryotes

M Sauer, M Heilemann - Chemical reviews, 2017 - ACS Publications
Super-resolution fluorescence imaging by photoactivation or photoswitching of single
fluorophores and position determination (single-molecule localization microscopy, SMLM) …

[HTML][HTML] Single-molecule localization microscopy

M Lelek, MT Gyparaki, G Beliu, F Schueder… - Nature reviews …, 2021 - nature.com
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …

Localization microscopy coming of age: from concepts to biological impact

M Sauer - Journal of cell science, 2013 - journals.biologists.com
Super-resolution fluorescence imaging by single-molecule photoactivation or
photoswitching and position determination (localization microscopy) has the potential to …

Fluorogenic dimers as bright switchable probes for enhanced super-resolution imaging of cell membranes

IO Aparin, R Yan, R Pelletier, AA Choi… - Journal of the …, 2022 - ACS Publications
Super-resolution fluorescence imaging based on single-molecule localization microscopy
(SMLM) enables visualizing cellular structures with nanometric precision. However, its …

[HTML][HTML] Optimizing imaging conditions for demanding multi-color super resolution localization microscopy

L Nahidiazar, AV Agronskaia, J Broertjes… - PloS one, 2016 - journals.plos.org
Single Molecule Localization super-resolution Microscopy (SMLM) has become a powerful
tool to study cellular architecture at the nanometer scale. In SMLM, single fluorophore labels …

Spectrally resolved and functional super-resolution microscopy via ultrahigh-throughput single-molecule spectroscopy

R Yan, S Moon, SJ Kenny, K Xu - Accounts of chemical research, 2018 - ACS Publications
Conspectus As an elegant integration of the spatial and temporal dimensions of single-
molecule fluorescence, single-molecule localization microscopy (SMLM) overcomes the …