Cholesterol is a fundamental molecule necessary for the maintenance of cell structure and is
vital to various normal biological functions. It is a key factor in lifestyle-related diseases …

Cholesterol dyshomeostasis in cancer cells leads to intracellular cholesterol accumulation,
which imparts drug resistance and allows these cells to evade apoptotic signalling …

Cholesterol is an essential structural component of membranes that contributes to
membrane integrity and fluidity. Cholesterol homeostasis plays a critical role in the …

The roles played by cholesterol in cancer development and the potential of therapeutically
targeting cholesterol homeostasis is a controversial area in the cancer community. Several …

Based on the structural and signaling roles of cholesterol, which are necessary for immune
cell activity, high concentrations of cholesterol and its metabolites not only trigger malignant …

Cholesterol is a ubiquitous sterol with many biological functions, which are crucial for proper
cellular signaling and physiology. Indeed, cholesterol is essential in maintaining membrane …

Cholesterol is a lipid molecule that plays an essential role in a number of biological
processes, both physiological and pathological. It is an essential structural constituent of cell …

While the unique metabolic activities of malignant tissues as potential targets for cancer
therapeutics has been the subject of several recent reviews, the role of cholesterol …

Cholesterol has been implicated in the pathophysiology and progression of several cancers
now, although the mechanisms by which it influences cancer biology are just emerging. Two …

Despite extensive research in the cancer field, cancer remains one of the most prevalent
diseases. There is an urgent need to identify specific targets that are safe and effective for …