Association of serum antibodies to herpes simplex virus 1 with cognitive deficits in individuals with schizophrenia

FB Dickerson, JJ Boronow, C Stallings… - Archives of general …, 2003 - jamanetwork.com
Background Cognitive deficits are a characteristic feature of schizophrenia and contribute to
the profound disabilities associated with this illness. Some of the cognitive deficits that occur …

Infection with herpes simplex virus type 1 is associated with cognitive deficits in bipolar disorder

FB Dickerson, JJ Boronow, C Stallings, AE Origoni… - Biological …, 2004 - Elsevier
BACKGROUND: In a previous investigation, we found an association between reduced
cognitive functioning and the prevalence of antibodies to herpes simplex virus type 1 in …

Serological evidence of exposure to Herpes Simplex Virus type 1 is associated with cognitive deficits in the CATIE schizophrenia sample

RH Yolken, EF Torrey, JA Lieberman, S Yang… - Schizophrenia …, 2011 - Elsevier
Cognitive impairment is a core feature of schizophrenia. Previous studies have indicated
that exposure to neurotropic infectious agents such as Herpes Simplex Virus type 1 may …

Neuroanatomic and cognitive abnormalities related to herpes simplex virus type 1 in schizophrenia

DJ Schretlen, TD Vannorsdall, JM Winicki… - Schizophrenia …, 2010 - Elsevier
Herpes simplex virus 1 (HSV-1) tends to replicate in the temporal cortex and can damage
the limbic system. The presence of serum antibodies to HSV-1 is associated with cognitive …

Deficit schizophrenia: association with serum antibodies to cytomegalovirus

F Dickerson, B Kirkpatrick, J Boronow… - Schizophrenia …, 2006 - academic.oup.com
Background: Patients with deficit schizophrenia differ from nondeficit patients with
schizophrenia relative to several neurobiological correlates and relative to the risk factors of …

Exposure to herpes simplex virus, type 1 and reduced cognitive function

P Thomas, T Bhatia, D Gauba, J Wood, C Long… - Journal of psychiatric …, 2013 - Elsevier
Herpes simplex virus, type 1 (HSV-1) causes cold sores, keratitis and rarely, fatal
encephalitis. The infection is lifelong, with sensory ganglia serving as reservoirs of latent …

Exposure to herpes simplex virus type 1 and cognitive impairments in individuals with schizophrenia

KM Prasad, AMM Watson, FB Dickerson… - Schizophrenia …, 2012 - academic.oup.com
Latent infection with neurotropic herpes viruses, such as herpes simplex virus, type 1
(HSV1), has been generally considered benign in most immunocompetent individuals …

Antibodies to cytomegalovirus and Herpes Simplex Virus 1 associated with cognitive function in schizophrenia

BH Shirts, KM Prasad, MF Pogue-Geile… - Schizophrenia …, 2008 - Elsevier
BACKGROUND:: Cognitive impairment in the form of decreased working memory and
executive functions has been recognized as a key deficit in schizophrenia. Neurotropic …

Progressive gray matter loss and changes in cognitive functioning associated with exposure to herpes simplex virus 1 in schizophrenia: a longitudinal study

KM Prasad, SM Eack, D Goradia… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: Longitudinal changes in gray matter volume and cognitive performance were
evaluated among individuals exposed to neurotropic herpes simplex virus subtype 1 …

Persistent infection with neurotropic herpes viruses and cognitive impairment

AMM Watson, KM Prasad, L Klei, JA Wood… - Psychological …, 2013 - cambridge.org
BackgroundHerpes virus infections can cause cognitive impairment during and after acute
encephalitis. Although chronic, latent/persistent infection is considered to be relatively …