[HTML][HTML] EGFR interacts with the fusion protein of respiratory syncytial virus strain 2-20 and mediates infection and mucin expression
MG Currier, S Lee, CC Stobart, AL Hotard… - PLoS …, 2016 - journals.plos.org
Respiratory syncytial virus (RSV) is the major cause of viral lower respiratory tract illness in
children. In contrast to the RSV prototypic strain A2, clinical isolate RSV 2–20 induces …
children. In contrast to the RSV prototypic strain A2, clinical isolate RSV 2–20 induces …
The respiratory syncytial virus fusion protein and neutrophils mediate the airway mucin response to pathogenic respiratory syncytial virus infection
KL Stokes, MG Currier, K Sakamoto, S Lee… - Journal of …, 2013 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is the leading cause of death due to a viral etiology in
infants. RSV disease is characterized by epithelial desquamation, neutrophilic bronchiolitis …
infants. RSV disease is characterized by epithelial desquamation, neutrophilic bronchiolitis …
Identification of residues in the human respiratory syncytial virus fusion protein that modulate fusion activity and pathogenesis
AL Hotard, S Lee, MG Currier, JE Crowe Jr… - Journal of …, 2015 - Am Soc Microbiol
Human respiratory syncytial virus (RSV) lower respiratory tract infection can result in
inflammation and mucus plugging of airways. RSV strain A2-line19F induces relatively high …
inflammation and mucus plugging of airways. RSV strain A2-line19F induces relatively high …
A chimeric A2 strain of respiratory syncytial virus (RSV) with the fusion protein of RSV strain line 19 exhibits enhanced viral load, mucus, and airway dysfunction
ML Moore, MH Chi, C Luongo, NW Lukacs… - Journal of …, 2009 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is the leading cause of respiratory failure and viral death in
infants. Abundant airway mucus contributes to airway obstruction in RSV disease …
infants. Abundant airway mucus contributes to airway obstruction in RSV disease …
Respiratory syncytial virus—viral biology and the host response
D Hacking, J Hull - Journal of infection, 2002 - Elsevier
Respiratory syncytial virus (RSV) is the most important cause of respiratory tract infection in
infants. We have an incomplete understanding of the reasons why some infants are more …
infants. We have an incomplete understanding of the reasons why some infants are more …
Respiratory syncytial virus F and G proteins induce interleukin 1α, CC, and CXC chemokine responses by normal human bronchoepithelial cells
CM Oshansky, JP Barber, J Crabtree… - The Journal of …, 2010 - academic.oup.com
Human respiratory syncytial virus (RSV) is a ubiquitous respiratory virus that causes serious
lower respiratory tract disease in infants and young children worldwide. Studies have shown …
lower respiratory tract disease in infants and young children worldwide. Studies have shown …
[HTML][HTML] CX3CR1 is expressed in differentiated human ciliated airway cells and co-localizes with respiratory syncytial virus on cilia in a G protein-dependent manner
KI Jeong, PA Piepenhagen, M Kishko, JM DiNapoli… - PloS one, 2015 - journals.plos.org
Respiratory syncytial virus (RSV) is the principal cause of bronchiolitis in infants and a
significant healthcare problem. The RSV Glycoprotein (G) mediates attachment of the virus …
significant healthcare problem. The RSV Glycoprotein (G) mediates attachment of the virus …
Mucosal vaccines against respiratory syncytial virus
K Yang, SM Varga - Current opinion in virology, 2014 - Elsevier
Highlights•New developments in RSV fusion (F) protein structure research.•The importance
of mucosal immunity in mediating protection against RSV infection.•Mucosal RSV vaccine …
of mucosal immunity in mediating protection against RSV infection.•Mucosal RSV vaccine …
Differential pathogenesis of respiratory syncytial virus clinical isolates in BALB/c mice
KL Stokes, MH Chi, K Sakamoto, DC Newcomb… - Journal of …, 2011 - Am Soc Microbiol
Airway mucus is a hallmark of respiratory syncytial virus (RSV) lower respiratory tract illness.
Laboratory RSV strains differentially induce airway mucus production in mice. Here, we …
Laboratory RSV strains differentially induce airway mucus production in mice. Here, we …
Respiratory syncytial virus attachment glycoprotein contribution to infection depends on the specific fusion protein
J Meng, AL Hotard, MG Currier, S Lee… - Journal of …, 2016 - Am Soc Microbiol
Human respiratory syncytial virus (RSV) is an important pathogen causing acute lower
respiratory tract disease in children. The RSV attachment glycoprotein (G) is not required for …
respiratory tract disease in children. The RSV attachment glycoprotein (G) is not required for …