A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis

L Wang, H Huang, X Li, L Ouyang, X Wei, J Xie, D Liu… - Chinese Medicine, 2023 - Springer
Ferroptosis is a non-apoptotic form of regulated cell death characterized by iron-dependent
lipid peroxidation. It can be triggered by various mechanisms, including the glutathione …

Targeting Ferroptosis in Cancer by Natural Products: An Updated Review

Z Guo, S Wang, H Hao, X Deng, J Fu… - The American Journal …, 2023 - World Scientific
Ferroptosis is a new cell death process characterized by massive iron accumulation and
lipid peroxidation. Emerging evidence demonstrates that ferroptosis plays a crucial role in …

[HTML][HTML] The mechanism of ferroptosis and applications in tumor treatment

X Lin, J Ping, Y Wen, Y Wu - Frontiers in Pharmacology, 2020 - frontiersin.org
Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid
peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of …

[HTML][HTML] Ferroptosis: Opportunities and Challenges in Cancer

YJ Jia, Y Zhang, XB Ma, Y Wang… - Journal of …, 2023 - xiahepublishing.com
Ferroptosis is a programmed cell death mainly manifested as accumulation of ferrous ions
and cell lipid peroxidation. Ferroptosis is well regulated by multiple signaling pathways, of …

TCM targets ferroptosis: potential treatments for cancer

L Qin, Y Zhong, Y Li, Y Yang - Frontiers in Pharmacology, 2024 - frontiersin.org
Ferroptosis is caused by the accumulation of cellular reactive oxygen species that exceed
the antioxidant load that glutathione (GSH) and phospholipid hydroperoxidases with GSH …

Recent progress on targeting ferroptosis for cancer therapy

G Xu, H Wang, X Li, R Huang, L Luo - Biochemical Pharmacology, 2021 - Elsevier
Ferroptosis is a new mode of cell death different from cell necrosis, autophagy, apoptosis,
and pyroptosis, which depends on the accumulation of reactive oxygen species (ROS) …

Ferroptosis: From regulation of lipid peroxidation to the treatment of diseases

Y Lv, M Wu, Z Wang, J Wang - Cell Biology and Toxicology, 2023 - Springer
Ferroptosis is a regulated cell death mainly manifested by iron-dependent lipid peroxide
accumulation. The leading cause of ferroptosis is the imbalance of intracellular oxidative …

Ferroptosis: a novel cell death form will be a promising therapy target for diseases

D Wu, L Chen - Acta biochimica et biophysica Sinica, 2015 - academic.oup.com
Recently, Friedmann Angeli et al.[1] reported that the loss of ferroptosis regulation enzyme
glutathione peroxidase 4 (GPX4) will cause an overwhelming ferroptosis of renal cells …

[HTML][HTML] Current understanding of phytochemicals from Chinese herbal medicines for ferroptosis-mediated cancer prevention and treatment

Y Hu, W Zhai, H Chen, L Li, W Gao, Y Wei… - … Research-Modern Chinese …, 2022 - Elsevier
Ferroptosis, which has attracted much attention, is a new form of regulated cell death that is
closely associated with the progression of various diseases. Ferroptosis is dependent upon …

Ferroptosis: The entanglement between traditional drugs and nanodrugs in tumor therapy

K Liu, L Huang, S Qi, S Liu, W Xie, L Du… - Advanced …, 2023 - Wiley Online Library
Ferroptosis is a non‐apoptotic programmed cell death caused by the accumulation of lipid
peroxide. System Xc‐/glutathione peroxidase 4 (GPX4) axis and iron axis are two main …