582 CORRESPONDENCE Pathology (2018), 50 (5), August (four copies) and IGH (3e7
copies). There was deletion of TP53 (two copies TP53 versus four copies 17q11) in 93% of …

To the Editor, Multiple myeloma is a bone marrow malignancy of plasma cells. It is
characterised by cytogenetic abnormalities, some of which have well established impact on …

A diagnosis of plasma cell neoplasm on histology is usually straightforward. However,
plasma cell neoplasms may occasionally display unusual phenotypic expression. 1 For …

Sir, The neoplastic cells of multiple myeloma have a broad morphological spectrum ranging
from neoplastic cells identical to mature plasma cells, to markedly pleomorphic and …

1. San Miguel JF, Schlag R, Khuagheva N et al. Bortezomib plus melphalan and prednisone
for initial treatment of multiple myeloma. N. Engl. J. Med. 2008; 359; 906–917. 2. Boyer JE …

5. Na HY, Choe JY, Shin SA, et al. Characteristics of CD5-positive diffuse large B-cell
lymphoma among Koreans: high incidence of BCL2 and MYC double-expressors. PLoS …

694 CORRESPONDENCE Pathology (2010), 42 (7), December publication by Yong et al. on
a case of myelinoid bodies in minimal change renal disease. 1 A 51-year-old male …

With the advent of imatinib as a first line agent for chronic myelogenous leukaemia (CML),
several studies have described morphological changes in marrows of imatinib-treated …

1. Nahi H, Sutlu T, Jansson M, et al. Clinical impact of chromosomal aberrations in multiple
myeloma. J Int Med 2011; 269: 137e47. 2. Kalff A, Spencer A. The t (4; 14) translocation and …

A 48-year-old man presented with several months of weakness, arthralgias, exertional
dyspnea and weight loss. On examination, generalised lymphadenopathy, moderate …