Background Psoriasis is a multifactorial disease arises from a complex interaction of
genetics, immune system, and environmental aspects. IL-23/Th17 immune axis has been …

Psoriasis is an autoimmune disease that is characterized by discolored, scaled patches of
skin. Clinically, it is found that psychological factors often induce or aggravate the disease …

Psoriatic skin contains more nerve fibers (Naukkarinen et al., 1989), has increased levels of
sensory nerve-derived calcitonin gene related peptide (CGRP) and substance P (SP)(Chan …

Background: Cannabinoid receptor 2 (CB2R) is a potential target for anti-inflammatory and
pain therapeutics given its significant immunomodulatory and analgesic effects. However …

Background: Hypertrophic scar formation may be related to cutaneous neurogenic
inflammation (CNI) through the substance P-neurokinin 1 receptor (SP-NK1R) signaling …

Background There is increasing evidence that neuropeptides may be involved in the
pathogenesis of atopic dermatitis (AD). Objectives To investigate the effects of tacrolimus on …

Background The nervous system contributes to inflammatory skin diseases. Objective The
aim of this investigation was to study the neuronal contribution to psoriasis at the remission …

Psoriasis is one of the most common chronic inflammatory diseases that is characterized by
well-defined erythematous plaques, with typical histopathological findings of lymphocytic …

Background The involvement of the nerve in psoriasis development was suggested by
sporadic case reports. Objectives To provide multiple evidence for the nerve in psoriasis …

Psoriasis is an unchecked chronic inflammation characterized by thick, erythematous, and
scaly plaques on the skin. The role of innate immune cells in the pathogenesis of psoriasis is …