Recent advances in the combination of cellular therapy with stem cells and nanoparticles after a spinal cord injury

E García, S Sánchez-Noriega… - Frontiers in …, 2023 - frontiersin.org
Background Currently, combined therapies could help to reduce long-term sequelae of
spinal cord injury (SCI); stem cell therapy at the site of injury in combination with other …

Combination therapy using nanomaterials and stem cells to treat spinal cord injuries

A Zarepour, AB Öztürk, DK Irmak, G Yaşayan… - European Journal of …, 2022 - Elsevier
As a part of the central nervous system, the spinal cord (SC) provides most of the
communications between the brain and other parts of the body. Any damage to SC interrupts …

Stem cells therapy for spinal cord injury: an overview of clinical trials

S Silvestro, P Bramanti, O Trubiani… - International Journal of …, 2020 - mdpi.com
Spinal cord injury (SCI) is a traumatic lesion that causes disability with temporary or
permanent sensory and/or motor deficits. The pharmacological approach still in use for the …

Recent therapeutic strategies for spinal cord injury treatment: possible role of stem cells

D Garbossa, M Boido, M Fontanella, C Fronda… - Neurosurgical …, 2012 - Springer
Spinal cord injury (SCI) often results in significant dysfunction and disability. A series of
treatments have been proposed to prevent and overcome the formation of the glial scar and …

Clinical trials of stem cell treatment for spinal cord injury

K Yamazaki, M Kawabori, T Seki, K Houkin - International Journal of …, 2020 - mdpi.com
There are more than one million patients worldwide suffering paralysis caused by spinal
cord injury (SCI). SCI causes severe socioeconomic problems not only to the patients and …

Concomitant use of mesenchymal stem cells and neural stem cells for treatment of spinal cord injury: a combo cell therapy approach

SM Hosseini, M Sani, KH Haider, M Dorvash… - Neuroscience …, 2018 - Elsevier
Abstract Treatment: with neural stem cells (NSCs) provides a hope to recover the neural
damage and compensate for the lost neural structures for restoration of interrupted neural …

Filling the gap: neural stem cells as a promising therapy for spinal cord injury

IM Pereira, A Marote, AJ Salgado, NA Silva - Pharmaceuticals, 2019 - mdpi.com
Spinal cord injury (SCI) can lead to severe motor, sensory and social impairments having a
huge impact on patients' lives. The complex and time-dependent SCI pathophysiology has …

An update on application of nanotechnology and stem cells in spinal cord injury regeneration

K Nejati-Koshki, Y Mortazavi… - Biomedicine & …, 2017 - Elsevier
Spinal cord injury (SCI) is damage to the spinal cord that leads to sudden loss of motor and
autonomic function and sensory under the level of the injury. The pathophysiological …

[HTML][HTML] Advances in neural stem cell therapy for spinal cord injury: safety, efficacy, and future perspectives

S Lee, H Nam, KM Joo, SH Lee - Neurospine, 2022 - ncbi.nlm.nih.gov
Spinal cord injury (SCI) is a devastating central nervous system injury that leads to severe
disabilities in motor and sensory functions, causing significant deterioration in patients' …

[HTML][HTML] Association between Neural Stem/Progenitor Cells and Biomaterials in Spinal Cord Injury Therapies: A Systematic Review and Network Meta-Analysis

J Jeon, SH Park, J Choi, SM Han, HW Kim, SR Shim… - Acta Biomaterialia, 2024 - Elsevier
Spinal cord injury (SCI) is associated with substantial healthcare challenges, frequently
resulting in enduring sensory and motor deficits alongside various chronic complications …