Inhibition of angiogenesis by IL-32: possible role in asthma

N Meyer, J Christoph, H Makrinioti, P Indermitte… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: IL-32 is a proinflammatory cytokine involved in various chronic
inflammatory diseases. Chronic airway inflammation in asthmatic patients results in …

Interleukin-32γ suppresses allergic airway inflammation in mouse models of asthma

BR Bang, HS Kwon, SH Kim, SY Yoon… - American Journal of …, 2014 - atsjournals.org
Asthma is a chronic airway inflammatory disease typically associated with T helper cell type
2 (Th2) cytokines. IL-32, first reported as an inducer of tumor necrosis factor (TNF)-α, is an …

Interleukin-32: its role in asthma and potential as a therapeutic agent

T Xin, M Chen, L Duan, Y Xu, P Gao - Respiratory Research, 2018 - Springer
Abstract Interleukin (IL)-32, also named natural killer cell transcript 4 (NK4), has increasingly
been described as an immunoregulator that controls cell differentiation and cell death and is …

Levels of IL-32 in serum, induced sputum supernatant, and bronchial lavage fluid of patients with chronic obstructive pulmonary disease

E Gasiuniene, S Lavinskiene… - COPD: Journal of …, 2016 - Taylor & Francis
ABSTRACT Interleukin-32 (IL-32) is a newly described cytokine which is expected to have
an important role in autoimmune disorders. It was shown that chronic obstructive pulmonary …

IL-32, a novel proinflammatory cytokine in chronic obstructive pulmonary disease

F Calabrese, S Baraldo, E Bazzan… - American journal of …, 2008 - atsjournals.org
Rationale: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory
disorder of the lung, yet the mechanisms that regulate this immune-inflammatory response …

Oxidative stress induced interleukin-32 mRNA expression in human bronchial epithelial cells

M Kudo, E Ogawa, D Kinose, A Haruna… - Respiratory …, 2012 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterized by airflow
obstruction and persistent inflammation in the airways and lung parenchyma. Oxidative …

IL-32 promotes angiogenesis

CA Nold-Petry, I Rudloff, Y Baumer, M Ruvo… - The Journal of …, 2014 - journals.aai.org
IL-32 is a multifaceted cytokine with a role in infections, autoimmune diseases, and cancer,
and it exerts diverse functions, including aggravation of inflammation and inhibition of virus …

IL-33 promotes airway remodeling and is a marker of asthma disease severity

Z Guo, J Wu, J Zhao, F Liu, Y Chen, L Bi, S Liu… - Journal of …, 2014 - Taylor & Francis
Objective: To investigate the function of interleukin-33 (IL-33) in the asthmatic airway
remodeling and the relationship between IL-33 and asthma severity. Methods: IL-33 levels …

Molecular characterization of IL-32 in human endothelial cells

H Kobayashi, PC Lin - Cytokine, 2009 - Elsevier
IL-32 is a newly discovered protein found in human and certain primates, but absent in
rodent. Various reports suggest its role as a proinflammatory mediator. Since vascular …

Expression of IL-32 in human lung cancer is related to the histotype and metastatic phenotype

C Sorrentino, E Di Carlo - American journal of respiratory and critical …, 2009 - atsjournals.org
Rationale: A strong link has been recently demonstrated between inflammation and lung
cancer. Thus, we investigated whether the proinflammatory cytokine IL-32 may be involved …