Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) have served as
prototypes for growth factor and receptor tyrosine kinase function for more than 25 years …

Platelet-derived growth factors (PDGFs) are soluble proteins that mediate intercellular
signaling via receptor tyrosine kinases. The patterns of PDGF and PDGF receptor …

Platelet‐derived growth factor (PDGF) was originally identified in platelets and in serum as a
mitogen for fibroblasts, smooth muscle cells (SMC) and glia cells in culture. PDGF has since …

Genetic analyses in mice have contributed significantly to the understanding of the
physiological functions of platelet-derived growth factors (PDGFs) and their receptors …

Platelet‐derived growth factor (PDGF) was one of the first growth factors to be characterized,
and the PDGF family of ligand and receptors has remained an archetype system for studies …

Members of the platelet-derived growth factor (PDGF) family are well known to be involved
in different pathological conditions. The cellular and molecular mechanisms induced by the …

The platelet-derived growth factor (PDGF)/PDGFR receptor (PDGFR) family is essential for a
vast array of physiological processes such as migration and proliferation of percityes that …

Platelet-derived growth factor (PDGF) is a critical regulator of mesenchymal cell migration
and proliferation. The vital functions of PDGFs for angiogenesis, as well as development of …

Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are frequently
expressed in various tumors and their expression levels correlate with tumor growth …

Platelet-derived growth factor (PDGF) was one of the first polypeptide growth factors
identified that signals through a cell surface tyrosine kinase receptor (PDGF-R) to stimulate …