Exploration beyond osteoarthritis: the association and mechanism of its related comorbidities
B Li, Z Yang, Y Li, J Zhang, C Li, N Lv - Frontiers in Endocrinology, 2024 - frontiersin.org
Osteoarthritis is the most prevalent age-related degenerative joint disease and a leading
cause of pain and disability in aged people. Its etiology is multifaceted, involving factors …
cause of pain and disability in aged people. Its etiology is multifaceted, involving factors …
Pathophysiological landscape of osteoarthritis
P Kulkarni, A Martson, R Vidya, S Chitnavis… - Advances in clinical …, 2021 - Elsevier
A sharp rise in osteoarthritis (OA) incidence is expected as over 25% of world population
ages in the coming decade. Although OA is considered a degenerative disease, mounting …
ages in the coming decade. Although OA is considered a degenerative disease, mounting …
Fundamentals of osteoarthritis: Inflammatory mediators in osteoarthritis
A De Roover, A Escribano-Núñez… - Osteoarthritis and …, 2023 - Elsevier
Objectives As more has become known of the pathophysiology of osteoarthritis (OA),
evidence that inflammation plays a critical role in its development and progression has …
evidence that inflammation plays a critical role in its development and progression has …
[HTML][HTML] Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …
more than 500 million population worldwide. OA was believed to be caused by the wearing …
[HTML][HTML] Systemic osteoarthritis: the difficulty of categorically naming a continuous condition
G Herrero-Beaumont, F Castro-Dominguez… - Aging Clinical and …, 2024 - Springer
Osteoarthritis (OA) is a disease with systemic implications that go beyond joint problems. Its
pathogenic mechanisms involve a variety of systemic conditions that contribute to joint …
pathogenic mechanisms involve a variety of systemic conditions that contribute to joint …
Osteoarthritis and type 2 diabetes: From pathogenetic factors to therapeutic intervention
F Cannata, G Vadalà, L Ambrosio… - Diabetes/metabolism …, 2020 - Wiley Online Library
Over the last decades, osteoarthritis (OA) and type 2 diabetes (T2D) prevalence increased
due to the global ageing population and the pandemic obesity. They currently affect a …
due to the global ageing population and the pandemic obesity. They currently affect a …
[HTML][HTML] Bridging Disciplines as a pathway to Finding New Solutions for Osteoarthritis a collaborative program presented at the 2019 Orthopaedic Research Society …
Objective To stimulate future research directions that seek solutions for osteoarthritis (OA) at
the interface between diverse disciplines and address osteoarthritis (OA) as a serious …
the interface between diverse disciplines and address osteoarthritis (OA) as a serious …
The intriguing intersection of type 2 diabetes, obesity-related insulin resistance, and osteoarthritis
D Bradley - The Journal of Clinical Endocrinology & Metabolism, 2021 - academic.oup.com
Osteoarthritis (OA) is characterized by degeneration of hyaline joint cartilage, hypertrophic
changes to the joint capsule, and damage to underlying bone with subchondral remodeling …
changes to the joint capsule, and damage to underlying bone with subchondral remodeling …
[HTML][HTML] Roles of hormone replacement therapy and menopause on osteoarthritis and cardiovascular disease outcomes: a narrative review
Osteoarthritis (OA) is a highly prevalent condition characterized by degradation of the joints.
OA and cardiovascular disease (CVD) are leading contributors to disease burden …
OA and cardiovascular disease (CVD) are leading contributors to disease burden …
[HTML][HTML] Obesity, Metabolic Syndrome, and Osteoarthritis Require Integrative Understanding and Management
Osteoarthritis (OA) is a progressive chronic disease affecting the articular joints, leading to
pain and disability. Unlike traditional views that primarily link OA to aging, recent …
pain and disability. Unlike traditional views that primarily link OA to aging, recent …