Gene therapy is a very attractive strategy in experimental cancer therapy. Ideally, the
approach aims to deliver therapeutic genes selectively to cancer cells. However, progress in …

Gene therapy is a very attractive strategy in experimental cancer therapy. Ideally, the
approach aims to deliver therapeutic genes selectively to cancer cells. However, progress in …

Gene therapy is reaching a stage where some clinical benefits have been demonstrated on
patients involved in phase I/II clinical trials. However, in many cases, the clinical benefit is …

Several methods are available for non-invasive imaging of gene delivery and transgene
expression, including magnetic resonance imaging (MRI), single photon emission …

For more than a decade, molecular imaging (MI) has increasingly been used to successfully
image gene expression in living animals, thus making significant contributions to the field of …

Noninvasive reporter gene imaging is a component of molecular imaging. Reporter imaging
can provide noninvasive assessments of endogenous biologic processes in living subjects …

Thus far, traditional methods for evaluating gene transfer and expression have been shown
to be of limited value in the clinical arena. Consequently there is a real need to develop new …

Recent progress in the development of noninvasive imaging technologies should allow
molecular imaging to play a major role in the field of gene therapy. These tools have recently …

Molecular imaging of gene expression in living subjects is leading to significant advances in
the field of gene therapy. Three different technologies have been utilized for monitoring …

Molecular-genetic imaging of cancer using nonviral delivery systems has great potential for
clinical application as a safe, efficient, noninvasive tool for visualization of various cellular …