[HTML][HTML] Novel targeted therapies and immunotherapy for advanced thyroid cancers

GE Naoum, M Morkos, B Kim, W Arafat - Molecular cancer, 2018 - Springer
Thyroid cancer is a frequently encountered endocrine malignancy. Despite the favorable
prognosis of this disease, 15–20% of differentiated thyroid cancer (DTC) cases and most …

[HTML][HTML] Novel targeted therapies for metastatic thyroid cancer—a comprehensive review

M Al-Jundi, S Thakur, S Gubbi, J Klubo-Gwiezdzinska - Cancers, 2020 - mdpi.com
The knowledge on thyroid cancer biology has grown over the past decade. Thus, diagnostic
and therapeutic strategies to manage thyroid cancer are rapidly evolving. With new insights …

[HTML][HTML] Molecular basis and targeted therapy in thyroid cancer: Progress and opportunities

L Zhang, Q Feng, J Wang, Z Tan, Q Li, M Ge - Biochimica et Biophysica …, 2023 - Elsevier
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. Surgery,
chemotherapy, radiotherapy, and radioactive iodine (RAI) therapy are the standard TC …

[HTML][HTML] New therapies for advanced thyroid cancer

D Laha, N Nilubol, M Boufraqech - Frontiers in endocrinology, 2020 - frontiersin.org
Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …

Evolving molecularly targeted therapies for advanced-stage thyroid cancers

KC Bible, M Ryder - Nature Reviews Clinical Oncology, 2016 - nature.com
Increased understanding of disease-specific molecular targets of therapy has led to the
regulatory approval of two drugs (vandetanib and cabozantinib) for the treatment of …

Targeted therapy for advanced thyroid cancer: kinase inhibitors and beyond

ME Cabanillas, M Ryder, C Jimenez - Endocrine reviews, 2019 - academic.oup.com
The treatment of advanced thyroid cancer has undergone rapid evolution in the last decade,
with multiple kinase inhibitor drug approvals for each subtype of thyroid cancer and a …

[HTML][HTML] Therapeutic options for advanced thyroid cancer

A Jayarangaiah, G Sidhu, J Brown… - … journal of clinical …, 2019 - clinsurggroup.us
Thyroid cancer can be largely classified as well-differentiated, poorly differentiated,
medullary and anaplastic. Differentiated thyroid cancer (DTC) includes follicular and …

[HTML][HTML] Molecular alterations in thyroid cancer: from bench to clinical practice

E Tirrò, F Martorana, C Romano, SR Vitale, G Motta… - Genes, 2019 - mdpi.com
Thyroid cancer comprises different clinical and histological entities. Whereas differentiated
(DTCs) malignancies are sensitive to radioiodine therapy, anaplastic (ATCs) and medullary …

Targeted therapy in thyroid cancer: state of the art

L Valerio, L Pieruzzi, C Giani, L Agate, V Bottici… - Clinical oncology, 2017 - Elsevier
Thyroid cancer typically has a good outcome following standard treatments, which include
surgery, radioactive iodine ablation for differentiated tumours and treatment with thyrotropine …

[HTML][HTML] Treatment of advanced thyroid cancer with targeted therapies: ten years of experience

D Viola, L Valerio, E Molinaro, L Agate… - Endocrine-related …, 2016 - erc.bioscientifica.com
Thyroid cancer is rare, but it is the most frequent endocrine malignancy. Its prognosis is
generally favorable, especially in cases of well-differentiated thyroid cancers (DTCs), such …