Long-term culture of purified postnatal oligodendrocyte precursor cells: evidence for an intrinsic maturation program that plays out over months
Oligodendrocytes myelinate axons in the vertebrate central nervous system (CNS). They
develop from precursor cells (OPCs), some of which persist in the adult CNS. Adult OPCs …
develop from precursor cells (OPCs), some of which persist in the adult CNS. Adult OPCs …
Cell size control and a cell-intrinsic maturation program in proliferating oligodendrocyte precursor cells
We have used clonal analysis and time-lapse video recording to study the proliferative
behavior of purified oligodendrocyte precursor cells isolated from the perinatal rat optic …
behavior of purified oligodendrocyte precursor cells isolated from the perinatal rat optic …
Purification and characterization of adult oligodendrocyte precursor cells from the rat optic nerve
J Shi, A Marinovich, BA Barres - Journal of Neuroscience, 1998 - Soc Neuroscience
Oligodendrocyte precursor cells (OPCs) persist in substantial numbers in the adult brain in a
quiescent state suggesting that they may provide a source of new oligodendrocytes after …
quiescent state suggesting that they may provide a source of new oligodendrocytes after …
Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells
Oligodendrocytes are post-mitotic cells that myelinate axons in the vertebrate central
nervous system (CNS). They develop from proliferating oligodendrocyte precursor cells …
nervous system (CNS). They develop from proliferating oligodendrocyte precursor cells …
Astrocytes promote neurogenesis from oligodendrocyte precursor cells
PM Gaughwin, MA Caldwell… - European Journal of …, 2006 - Wiley Online Library
The oligodendrocyte precursor cell (OPC) has until recently been regarded as a lineage‐
restricted precursor cell. Considerable interest has been generated by reports suggesting …
restricted precursor cell. Considerable interest has been generated by reports suggesting …
Control of oligodendrocyte number in the developing rat optic nerve
BA Barres, MC Raff - Neuron, 1994 - Elsevier
The only known function of oligodendrocytes is to myelinate axons in the vertebrate CNS. In
this review, we consider how the number of oligodendrocytes is matched during …
this review, we consider how the number of oligodendrocytes is matched during …
Human oligodendrocyte precursor cells in vitro: phenotypic analysis and differential response to growth factors
HC Wilson, C Onischke, CS Raine - Glia, 2003 - Wiley Online Library
Following experimental demyelination in rodents, oligodendrocyte precursor cells (OPCs)
proliferate and differentiate into myelin‐producing oligodendrocytes which effect robust …
proliferate and differentiate into myelin‐producing oligodendrocytes which effect robust …
Axonal control of oligodendrocyte development
BA Barres, MC Raff - The Journal of cell biology, 1999 - rupress.org
HOW are the numbers of different cell types matched together during tissue development?
The nervous system has provided an excellent model system for understanding this …
The nervous system has provided an excellent model system for understanding this …
Oligodendrocyte precursor cells from different brain regions express divergent properties consistent with the differing time courses of myelination in these regions
J Power, M Mayer-Pröschel, J Smith, M Noble - Developmental biology, 2002 - Elsevier
Different CNS regions exhibit different temporal patterns of oligodendrocyte generation and
myelinogenesis. Characterization of oligodendrocyte-type-2 astrocyte progenitor cells (here …
myelinogenesis. Characterization of oligodendrocyte-type-2 astrocyte progenitor cells (here …
Differentiation and death of premyelinating oligodendrocytes in developing rodent brain
BD Trapp, A Nishiyama, D Cheng… - The Journal of cell …, 1997 - rupress.org
Previous studies have indicated that newly formed oligodendrocytes are dynamic cells
whose production, survival, and differentiation depend upon axonal influences. This study …
whose production, survival, and differentiation depend upon axonal influences. This study …