Background The positive association between obesity and postmenopausal breast cancer
has been attributed, in part, to the fact that estrogen, a risk factor for breast cancer, is …

Background: Insulin and insulin-like growth factor I (IGF-I) are important mitogens in vitro
and in vivo. It has been hypothesized that these factors may play an important role in the …

Postmenopausal overweight women have an increased risk of breast cancer. The link
between obesity and breast cancer could be mediated through hyperinsulinemia. Insulin …

A positive association between obesity and the risk of incident postmenopausal breast
cancer has been consistently observed in epidemiologic studies. Although most studies of …

Adiposity is an established risk factor for postmenopausal breast cancer. Recent data
suggest that high insulin levels in overweight women may play a major role in this …

We considered epidemiological data on overweight, diabetes, insulin, and breast cancer.
Overweight is inversely related to premenopausal breast cancer, but there is definite …

It is hypothesized that insulin resistance and related metabolic factors may influence breast
cancer risk, however the epidemiological evidence remains inconclusive. We conducted a …

BACKGROUND: Cross-cultural studies have long suggested that the high incidence of
breast cancer in developed Western countries may be linked to the high prevalence of …

Insulin‐like growth factor I (IGF‐I) is a systemic hormone with potent mitogenic and anti‐
apoptotic properties, which could influence the proliferative behavior of normal breast cells …

Objective: To assess the association between fasting insulin levels and breast cancer
Design: Cross sectional study Participants: 3868 women aged 60–79 years Main outcome …