Antiviral responses versus virus-induced cellular shutoff: a game of thrones between influenza A virus NS1 and SARS-CoV-2 Nsp1
AM Khalil, A Nogales, L Martínez-Sobrido… - Frontiers in Cellular …, 2024 - frontiersin.org
Following virus recognition of host cell receptors and viral particle/genome internalization,
viruses replicate in the host via hijacking essential host cell machinery components to evade …
viruses replicate in the host via hijacking essential host cell machinery components to evade …
The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies
The SARS-CoV-2 virus, the pathogen causing COVID-19, has caused more than 200 million
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …
Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution
Q Yang, AE Elz, M Panis, T Liu… - Frontiers in …, 2023 - frontiersin.org
Influenza A virus (IAV) is an important human respiratory pathogen that causes significant
seasonal epidemics and potential devastating pandemics. As part of its life cycle, IAV …
seasonal epidemics and potential devastating pandemics. As part of its life cycle, IAV …
Innate immunology in COVID-19—a living review. Part I: viral entry, sensing and evasion
The coronavirus infectious disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a world health concern and can …
respiratory syndrome coronavirus 2 (SARS-CoV-2) remains a world health concern and can …
SARS-CoV-2 within-host diversity of human hosts and its implications for viral immune evasion
B Xi, X Zeng, Z Chen, J Zeng, L Huang, H Du - MBio, 2023 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously evolving,
bringing great challenges to the control of the virus. In the present study, we investigated the …
bringing great challenges to the control of the virus. In the present study, we investigated the …
Innate immunity and influenza A virus pathogenesis: lessons for COVID-19
KL Hartshorn - Frontiers in Cellular and Infection Microbiology, 2020 - frontiersin.org
There is abundant evidence that the innate immune response to influenza A virus (IAV) is
highly complex and plays a key role in protection against IAV induced infection and illness …
highly complex and plays a key role in protection against IAV induced infection and illness …
Uncovering novel viral innate immune evasion strategies: what has SARS-CoV-2 taught us?
DJW Tay, ZZR Lew, JJH Chu, KS Tan - Frontiers in Microbiology, 2022 - frontiersin.org
The ongoing SARS-CoV-2 pandemic has tested the capabilities of public health and
scientific community. Since the dawn of the twenty-first century, viruses have caused several …
scientific community. Since the dawn of the twenty-first century, viruses have caused several …
SARS-CoV-2 non-structural proteins and their roles in host immune evasion
Coronavirus disease 2019 (COVID-19) has caused an unprecedented global crisis and
continues to threaten public health. The etiological agent of this devastating pandemic …
continues to threaten public health. The etiological agent of this devastating pandemic …
SARS-CoV-2 nsp15 endoribonuclease antagonizes dsRNA-induced antiviral signaling
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 has caused millions of
deaths since its emergence in 2019. Innate immune antagonism by lethal CoVs such as …
deaths since its emergence in 2019. Innate immune antagonism by lethal CoVs such as …
Insights into pandemic respiratory viruses: manipulation of the antiviral interferon response by SARS-CoV-2 and influenza A virus
Highlights•SARS-CoV-2 and influenza A virus (IAV) dysregulate human innate immune
responses.•Severe COVID-19 and severe influenza exhibit distinct cytokine …
responses.•Severe COVID-19 and severe influenza exhibit distinct cytokine …
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