Amine oxidase copper‐containing 3 aggravates cardiac remodelling by generating hydrogen peroxide after myocardial infarction
C Zhong, D Que, W Yu, D Chen, Y Wang… - The Journal of …, 2023 - Wiley Online Library
Amine oxidase copper‐containing 3 (AOC3) is a member of the semicarbazide‐sensitive
amine oxidase enzyme family. It acts as an ectoenzyme catalysing the oxidative …
amine oxidase enzyme family. It acts as an ectoenzyme catalysing the oxidative …
[HTML][HTML] Increased atherosclerotic plaque in AOC3 knock-out in ApoE−/− mice and characterization of AOC3 in atherosclerotic human coronary arteries
A Filip, S Taleb, R Bascetin, M Jahangiri… - Frontiers in …, 2022 - frontiersin.org
Introduction Amine oxidase copper containing 3 (AOC3) displays adhesion between
leukocytes and endothelial cells and enzymatic functions. Given its controversial role in …
leukocytes and endothelial cells and enzymatic functions. Given its controversial role in …
Amine oxidase activity regulates the development of pulmonary fibrosis
F Marttila‐Ichihara, K Elima, K Auvinen… - The FASEB …, 2017 - Wiley Online Library
In pulmonary fibrosis, an inflammatory reaction and differentiation of myofibroblasts
culminate in pathologic deposition of collagen. Amine oxidase copper containing‐3 (AOC3) …
culminate in pathologic deposition of collagen. Amine oxidase copper containing‐3 (AOC3) …
Semicarbazide‐Sensitive Amine Oxidase Increases in Calcific Aortic Valve Stenosis and Contributes to Valvular Interstitial Cell Calcification
N Mercier, SC Pawelzik, J Pirault… - Oxidative Medicine …, 2020 - Wiley Online Library
Introduction. Calcific aortic valve stenosis (CAVS) is a common disease associated with
aging. Oxidative stress participates in the valve calcification process in CAVS …
aging. Oxidative stress participates in the valve calcification process in CAVS …
ALDOA protects cardiomyocytes against H/R-induced apoptosis and oxidative stress by regulating the VEGF/Notch 1/Jagged 1 pathway
G Luo, R Wang, H Zhou, X Liu - Molecular and Cellular Biochemistry, 2021 - Springer
Myocardial infarction (MI) is a myocardial necrosis disease caused by continuous ischemia
and hypoxia. Abnormal expression of aldolase A (ALDOA) has been reported in cardiac …
and hypoxia. Abnormal expression of aldolase A (ALDOA) has been reported in cardiac …
Metabolomic and transcriptomic signatures of chemogenetic heart failure
F Spyropoulos, A Sorrentino… - American Journal …, 2022 - journals.physiology.org
The failing heart is characterized by elevated levels of reactive oxygen species. We have
developed an animal model of heart failure induced by chemogenetic production of …
developed an animal model of heart failure induced by chemogenetic production of …
Semicarbazide‐sensitive amine oxidase overexpression has dual consequences: insulin mimicry and diabetes‐like complications
C M. Stolen, R Madanat, L Marti, S Kari… - The FASEB …, 2004 - Wiley Online Library
Semicarbazide‐sensitive amine oxidases (SSAO) are copper‐containing enzymes that
oxidatively deaminate primary amines to produce hydrogen peroxide, ammonium, and …
oxidatively deaminate primary amines to produce hydrogen peroxide, ammonium, and …
Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in lipopolysaccharide-induced pulmonary inflammation
HY Peter, LX Lu, H Fan, M Kazachkov, ZJ Jiang… - The American journal of …, 2006 - Elsevier
Semicarbazide-sensitive amine oxidase (SSAO) resides on the vascular endothelium and
smooth muscle cell surface and is capable of deaminating short chain aliphatic amines and …
smooth muscle cell surface and is capable of deaminating short chain aliphatic amines and …
[HTML][HTML] Monoamine oxidase A-dependent ROS formation modulates human cardiomyocyte differentiation through AKT and WNT activation
M Di Sante, S Antonucci, L Pontarollo… - Basic Research in …, 2023 - Springer
During embryonic development, cardiomyocytes undergo differentiation and maturation,
processes that are tightly regulated by tissue-specific signaling cascades. Although redox …
processes that are tightly regulated by tissue-specific signaling cascades. Although redox …
Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl) allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase …
AM O'Rourke, EY Wang, A Miller, EM Podar… - … of Pharmacology and …, 2008 - ASPET
Semicarbazide-sensitive amine oxidase (SSAO, amine oxidase, copper-containing 3, and
vascular adhesion protein-1) is a copper-containing enzyme that catalyzes the oxidative …
vascular adhesion protein-1) is a copper-containing enzyme that catalyzes the oxidative …