[HTML][HTML] Connexin 43 mediates spread of Ca2+ -dependent proinflammatory responses in lung capillaries
K Parthasarathi, H Ichimura, E Monma… - The Journal of …, 2006 - Am Soc Clin Investig
Acute lung injury (ALI), which is associated with a mortality of 30–40%, is attributable to
inflammation that develops rapidly across the lung's vast vascular surface, involving an …
inflammation that develops rapidly across the lung's vast vascular surface, involving an …
Connexin43 modulates neutrophil recruitment to the lung
MZR Sarieddine, KEL Scheckenbach… - Journal of cellular …, 2009 - Wiley Online Library
Transmigration of neutrophils through the microvascular endothelium is a cardinal event of
acute inflammation. It has been suggested that gap junctions made of connexin43 (Cx43) …
acute inflammation. It has been suggested that gap junctions made of connexin43 (Cx43) …
[HTML][HTML] Gap junction protein connexin43 exacerbates lung vascular permeability
JJ O'Donnell III, AA Birukova, EC Beyer, KG Birukov - PloS one, 2014 - journals.plos.org
Increased vascular permeability causes pulmonary edema that impairs arterial oxygenation
and thus contributes to morbidity and mortality associated with Acute Respiratory Distress …
and thus contributes to morbidity and mortality associated with Acute Respiratory Distress …
Endothelial connexin43 mediates acid-induced increases in pulmonary microvascular permeability
K Parthasarathi - … Journal of Physiology-Lung Cellular and …, 2012 - journals.physiology.org
Acid aspiration, a common cause of acute lung injury, leads to alveolar edema. Increase in
lung vascular permeability underlies this pathology. To define mechanisms, isolated rat …
lung vascular permeability underlies this pathology. To define mechanisms, isolated rat …
Changes in endothelial connexin 43 expression inversely correlate with microvessel permeability and VE-cadherin expression in endotoxin-challenged lungs
K Kandasamy, R Escue, J Manna… - … of Physiology-Lung …, 2015 - journals.physiology.org
Endothelial barrier restoration reverses microvessel hyperpermeability and facilitates
recovery from lung injury. Because inhibiting connexin 43 (Cx43)-dependent …
recovery from lung injury. Because inhibiting connexin 43 (Cx43)-dependent …
Acute inflammation decreases the expression of connexin 40 in mouse lung
S Rignault, JA Haefliger, B Waeber, L Liaudet, F Feihl - Shock, 2007 - journals.lww.com
Transmigration of neutrophil polymorphonuclear leukocytes through the microvascular
endothelium is a cardinal event of acute inflammation. In vitro, this process can be restricted …
endothelium is a cardinal event of acute inflammation. In vitro, this process can be restricted …
Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo
LP Véliz, FG González, BR Duling… - American Journal of …, 2008 - journals.physiology.org
To assess the hypothesis that gap junctions (GJs) participate on leukocyte-endothelium
interactions in the inflammatory response, we compared leukocyte adhesion and …
interactions in the inflammatory response, we compared leukocyte adhesion and …
Monocyte–endothelial adhesion is modulated by Cx43-stimulated ATP release from monocytes
D Yuan, Q Wang, D Wu, M Yu, S Zhang, L Li… - Biochemical and …, 2012 - Elsevier
Adhesion of circulating monocytes to vascular endothelial cells is a crucial event in
development of vascular inflammatory conditions, including atherosclerosis. We investigated …
development of vascular inflammatory conditions, including atherosclerosis. We investigated …
Connexin 40 regulates lung endothelial permeability in acute lung injury via the ROCK1-MYPT1-MLC20 pathway
J Yin, L Lv, P Zhai, T Long, Q Zhou… - … of Physiology-Lung …, 2019 - journals.physiology.org
Increased pulmonary vascular permeability is a hallmark of acute lung injury (ALI). Connexin
40 (Cx40) is a gap junctional protein abundantly present in the lung microvascular …
40 (Cx40) is a gap junctional protein abundantly present in the lung microvascular …
[HTML][HTML] Macrophage Cx43 is necessary for fibroblast cytosolic calcium and lung fibrosis after injury
A Bhattacharyya, P Torre, P Yadav… - Frontiers in …, 2022 - frontiersin.org
Macrophages are paracrine signalers that regulate tissular responses to injury through
interactions with parenchymal cells. Connexin hemichannels have recently been shown to …
interactions with parenchymal cells. Connexin hemichannels have recently been shown to …