Drug repurposing represents an alternative therapeutic strategy to cancer treatment. The
potent anti-cancer activities of a FDA-approved anthelminthic drug niclosamide have been …

Background/Aim: Niclosamide is an antihe-minthic drug that has shown cytotoxic effects on
non-small cell lung carcinoma (NSCLC) cells. However, the exact mechanisms underlying …

Glioblastoma is the most common and lethal malignant primary brain tumor for which the
development of efficacious chemotherapeutic agents remains an urgent need. The anti …

Niclosamide is an oral chlorinated salicylanilide antihelminthic agent with potential
anticancer activity suggested in several cancer types, however, its anticancer action and …

The rapid development of new anticancer drugs that are safe and effective is a common goal
shared by basic scientists, clinicians and patients. The current review discusses one such …

Background: Ovarian carcinoma is a common malignant tumor of the female reproductive
organs with an incidence rate second only to cervical and endometrial cancers. In the past …

The morbidity of thyroid cancer has been rising obviously throughout the world during the
past years. Classic treatment procedure is generally curable for low risk differentiated thyroid …

Breast carcinoma is the most common female cancer with considerable metastatic potential.
Discovery of new therapeutic approaches for treatment of metastatic breast cancer is still …

Purpose To investigate the effects of anthelminthic drug niclosamide in renal cell carcinoma
(RCC) and the underlying mechanisms of its action. Methods The effects of niclosamide on …

Targeting mitochondria is an attractive strategy for cancer therapy due to the essential roles
of mitochondria in cancer cell energy metabolism. In this study, we show that mefloquine, an …