Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …

Plasma lipoprotein (a)[L p (a)] is a quantitative genetic trait with a very broad and skewed
distribution, which is largely controlled by genetic variants at the LPA locus on chromosome …

Background—Functional copy number variation in the apolipoprotein (a) gene (LPA)
underlies a variable number of protein kringle domains repeated in tandem in the lipoprotein …

LPA, the gene coding for apolipoprotein (a)[apo (a)], is the major determinant of lipoprotein
(a)[Lp (a)] plasma levels, which are associated with risk for coronary heart disease (CHD) …

High lipoprotein (a)[Lp (a)] concentrations are an independent risk factor for cardiovascular
outcomes. Concentrations are strongly influenced by apo (a) kringle IV repeat isoforms. We …

A high plasma concentration of lipoprotein (a)[Lp (a)] has been suggested as a risk factor for
coronary heart disease (CHD), but some recent prospective studies have questioned the …

High levels of lipoprotein (a)[Lp (a)], an apoB100-containing lipoprotein, are an independent
and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms …

Abstract Lipoprotein (a)[Lp (a)] is an independent risk factor for atherosclerosis-related
events that is under strong genetic control (heritability= 0.68–0.98). However, causal …

Objective: Lipoprotein (a)(Lp [a]) is associated with coronary artery disease (CAD) but also
to LDL (low-density lipoprotein) cholesterol. The genetic architecture of Lp (a) remains …

Abstract Lipoprotein (a)[Lp (a)] became besides LDL cholesterol one of the most attractive
targets for intervention in cardiovascular disease. Strong genetic evidence supports the …