In the broad range of human diseases, thrombo-inflammation appears as a clinical
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …

Platelets are well recognized as a key cell component of the hemostatic system. Recently,
several additional functions have been discovered for these blood cells but most importantly …

Besides mediating hemostatic functions, platelets are increasingly recognized as important
players of inflammation. Data from experiments in mice and men revealed various …

Platelets have classically been considered crucial effector cells in hemostasis, but now are
increasingly recognized as players during inflammatory responses in innate and adaptive …

For many years it has been known that platelets play an important role in thrombosis and
hemostasis. In recent times, however, it has become evident that platelets also have relevant …

There is accumulating evidence that platelets play roles beyond their traditional functions in
thrombosis and hemostasis, eg, in inflammatory processes, infection and cancer, and that …

The paradigm of platelets as mere mediators of hemostasis has long since been replaced by
a dual role: hemostasis and inflammation. Now recognized as key players in innate and …

Thrombosis and cardiovascular complications are common manifestations of a variety of
pathological conditions, including infections and chronic inflammatory diseases. Hence …

New findings highlight the complex interplay of innate immunity, coagulation and platelets in
inflammation and infection, and unravel novel molecular pathways and effector functions …

Platelets play central roles for maintaining the homeostasis of the blood coagulation. As they
are also involved in immune responses and host defenses, increasing evidences have …