Proceedings of the first curing coma campaign NIH symposium: challenging the future of research for coma and disorders of consciousness

J Claassen, Y Akbari, S Alexander, MK Bader, K Bell… - Neurocritical care, 2021 - Springer
Coma and disorders of consciousness (DoC) are highly prevalent and constitute a burden
for patients, families, and society worldwide. As part of the Curing Coma Campaign, the …

Proceedings of the second curing coma campaign NIH symposium: challenging the future of research for coma and disorders of consciousness

S Mainali, V Aiyagari, S Alexander, Y Bodien… - Neurocritical care, 2022 - Springer
This proceedings article presents actionable research targets on the basis of the
presentations and discussions at the 2nd Curing Coma National Institutes of Health (NIH) …

The Curing Coma Campaign: challenging the paradigm for disorders of consciousness

DWM Olson, JC Hemphill III… - Neurocritical Care, 2021 - Springer
Medicine has been concerned with coma since ancient times. The writings of Hippocrates
reference koma, which is Greek for “deep sleep,” and numerous medical writings from the …

The curing coma campaign: framing initial scientific challenges—proceedings of the first curing coma campaign scientific advisory council meeting

JJ Provencio, JC Hemphill, J Claassen, BL Edlow… - Neurocritical care, 2020 - Springer
Coma and disordered consciousness are common manifestations of acute neurological
conditions and are among the most pervasive and challenging aspects of treatment in …

Common data elements for disorders of consciousness: recommendations from the Working Group on Hospital Course, Confounders, and Medications

ME Barra, EK Zink, TP Bleck, E Cáceres, S Farrokh… - Neurocritical care, 2023 - Springer
The convergence of an interdisciplinary team of neurocritical care specialists to organize the
Curing Coma Campaign is the first effort of its kind to coordinate national and international …

Common data elements for disorders of consciousness: Recommendations from the working group on behavioral phenotyping

A Yakhkind, N Niznick, YG Bodien, FM Hammond… - Neurocritical care, 2023 - Springer
Background The recent publication of practice guidelines for management of patients with
disorders of consciousness (DoC) in the United States and Europe was a major step forward …

The curing coma campaign and the future of coma research

DWM Olson, JC Hemphill, JJ Provencio… - Seminars in …, 2022 - thieme-connect.com
Recovery from coma or disordered consciousness is a central issue in patients with acute
brain injuries such as stroke, trauma, cardiac arrest, and brain infections. Yet, major gaps …

Mechanisms underlying disorders of consciousness: bridging gaps to move toward an integrated translational science

AI Luppi, J Cain, LRB Spindler, UJ Górska, D Toker… - Neurocritical care, 2021 - Springer
Aim In order to successfully detect, classify, prognosticate, and develop targeted therapies
for patients with disorders of consciousness (DOC), it is crucial to improve our mechanistic …

Common data elements for disorders of consciousness: Recommendations from the working group on neuroimaging

BL Edlow, VL Boerwinkle, J Annen, M Boly… - Neurocritical care, 2023 - Springer
Background Over the past 5 decades, advances in neuroimaging have yielded insights into
the pathophysiologic mechanisms that cause disorders of consciousness (DoC) in patients …

A precision medicine framework for classifying patients with disorders of consciousness: Advanced Classification of Consciousness Endotypes (ACCESS)

D Kondziella, DK Menon, R Helbok, L Naccache… - Neurocritical Care, 2021 - Springer
Background Consciousness in patients with brain injury is traditionally assessed based on
semiological evaluation at the bedside. This classification is limited because of low …