Following single intragastric doses of d-and dl-[24C] norgestrel (Ng), rhesus monkeys
excreted 29.5+/-2.0 (SE) and 52.6+/-5.4% of the administered radioactivity in urine. Fecal …

SUMMARY [14 C] Norgestrel was administered to seven human subjects and 43% of dose
was excreted in the urine within 5 days; the biological half-life of the radioactivity was 24 hr …

Excretion data and urinary metabolite patterns of dl-. d-. and/-norgestrel were obtained from
women who received a single. oral 1. 5-mg dose of 14C-labeled racemic norgestrel (Ng) or …

Administration of norgestrel I (racemic 13β-ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one)
to humans has been shown by mass spectrometry and other analytical techniques to yield a …

The comparative metabolism of dl-, d-, and l-norgestrel was investigated in African Green
Monkeys (Cercopithecus aethiops). Total 14C excretion in urine after a single oral dose of …

the most potent progestational steroids; it is a totally synthetic compound and the prepa-
ration normally used is a mixture of the LandD forms, although only the latter is biologic-ally …

hydroxygon-4-en-3-one) is a mixture of 2 isomers, the D and L forms, due to the asymetric
centre at C13. Previous metabolism studies in humans (Littleton et al., 1968, J. Endocrin. 42 …

The excretion of radioactivity in the urine of four women, after oral administration of tritiated
17α-ethynyl-estr-5 (10)-ene-3-one-17β-o1 (norethynodrel) averaged 38 per cent of the …

SUMMARY After injection of [4-14 C] norethisterone or norgestrel labelled with 14 C in the
ethynyl group into rabbits, 45% and 57· 4% of the radioactivity was excreted in the urine …

A sensitive procedure, based on sulfuric acid-induced fluorescence, has been developed for
the analysis of norgestrel (dl-13-ethyl-17α-ethinyl-17-hydroxygon-4-en-3-one) in tablets of …