The circadian clock provides cue-independent anticipatory signals for diurnal rhythms of
baseline glucose levels and glucose tolerance. The central circadian clock is located in the …

The everyday life of mammals, including humans, exhibits many behavioral, physiological
and endocrine oscillations. The major timekeeping mechanism for these rhythms is …

The circadian system generates endogenous rhythms of approximately 24 h, the
synchronisation of which are vital for healthy bodily function. The timing of many …

The incidence of obesity and type 2 diabetes mellitus (T2DM) has risen to epidemic
proportions. The pathophysiology of T2DM is complex and involves insulin resistance …

The epidemic of Type 2 diabetes mellitus necessitates development of novel therapeutic
and preventative strategies to attenuate expansion of this debilitating disease. Evidence …

The circadian system serves one of the most fundamental properties present in nearly all
organisms: it generates 24-h rhythms in behavioral and physiological processes and …

Aims Recent studies suggest that circadian rhythms regulate glucose metabolism, weight
loss, and even drug efficacy. Moreover, molecules targeted at the circadian clock show …

The circadian clock is a biological timekeeping system to govern temporal rhythms of the
endocrine system and metabolism. The master pacemaker of biological rhythms is housed …

The mammalian circadian clock plays a central role in the temporal coordination of
physiology across the 24-h light-dark cycle. A major function of the clock is to maintain …

Completing the understanding of how genetic and environmental factors influence the
circadian clock and the effect these have on human circadian metabolic physiology and …