Aspirin, statins, and primary prevention: opportunities for shared decision making in the face of uncertainty

A Jhaveri, RA Sibley, ES Spatz, J Dodson - Current Cardiology Reports, 2021 - Springer
Abstract Purpose of Review The utility of aspirin and statins for primary prevention of
atherosclerotic cardiovascular disease remains ambiguous in older adults. Current …

Aspirin and statin therapy for primary prevention of cardiovascular disease in older adults

S Montgomery, MD Miedema, JA Dodson - Heart, 2022 - heart.bmj.com
The value of primary preventative therapies for cardiovascular disease (CVD) in older adults
(age≥ 75 years) is less certain than in younger patients. There is a lack of quality evidence …

[HTML][HTML] Older adult preferences regarding benefits and harms of statin and aspirin therapy for cardiovascular primary prevention

FM Wang, HG Yebyo, SH Ballew… - American journal of …, 2023 - Elsevier
Objective Personalizing preventive therapies for atherosclerotic cardiovascular disease
(ASCVD) is particularly important for older adults, as they tend to have multiple chronic …

Primary prevention of cardiovascular disease in older adults

AR Barry, DE O'Neill, MM Graham - Canadian Journal of Cardiology, 2016 - Elsevier
Primary prevention of cardiovascular events in older adults is challenging because of a
general paucity of evidence for safe and efficacious therapy. Furthermore, there is no …

Older Adult Perspectives on Statin Continuation and Discontinuation in Primary Cardiovascular Disease Prevention: A Mixed-Methods Study

L Brunner, B Mooser, A Spinewine… - Patient preference …, 2024 - Taylor & Francis
Background and Purpose Evidence for statin use for primary cardiovascular disease
prevention in older adults is limited. When evidence on risk-benefit profile of a medication is …

Primary prevention with statins in the elderly

MB Mortensen, E Falk - Journal of the American College of Cardiology, 2018 - jacc.org
The burden of atherosclerotic cardiovascular disease (ASCVD) in high-income countries is
mostly borne by the elderly. With increasing life expectancy, clear guidance on sensible use …

Statins for primary prevention in older adults—moving toward evidence‐based decision‐making

S Singh, S Zieman, AS Go, SP Fortmann… - Journal of the …, 2018 - Wiley Online Library
Objectives To determine the efficacy and safety of statins for primary prevention of
atherosclerotic cardiovascular disease (ASCVD) events in older adults, especially those …

Statins for the primary prevention of cardiovascular events in older adults: a review of the evidence

R Ali, KP Alexander - The American Journal of Geriatric Pharmacotherapy, 2007 - Elsevier
BACKGROUND:: Although statins have been demonstrated to be beneficial for secondary
prevention in the elderly, their use for primary prevention has not been well described …

Primary risk prevention in the elderly: use clinician-patient discussions, not automatic statin prescribing

NJ Stone, CB Blum - The American Journal of Medicine, 2015 - amjmed.com
Cholesterol management in the elderly is challenging owing to competing risks for mortality,
potential for interactions with more complex medical regimens, and the importance of safety …

Statin use in older adults for primary cardiovascular disease prevention across a spectrum of cardiovascular risk

A Sarraju, G Spencer-Bonilla, S Chung… - Journal of General …, 2021 - Springer
Background There remains uncertainty regarding optimal primary atherosclerotic
cardiovascular disease (ASCVD) prevention practices for older adults. Objective To assess …