[HTML][HTML] Targeted proteomics for evaluating risk of venous thrombosis following traumatic lower‐leg injury or knee arthroscopy

Y Mohammed, CE Touw, B Nemeth… - Journal of Thrombosis …, 2022 - Elsevier
Introduction Patients with lower‐leg cast immobilization and patients undergoing knee
arthroscopy have an increased risk of venous thrombosis (VT). Guidelines are ambiguous …

Enhanced in vivo and ex vivo thrombin generation after lower-leg trauma, but not after knee arthroscopy

CE Touw, B Nemeth, RA van Adrichem… - Thrombosis …, 2023 - Springer
Background There is room for improvement of prevention of venous thromboembolism (VTE)
after lower-leg cast application or knee arthroscopy. Information about the mechanism of clot …

Identification of thrombotic biomarkers in orthopedic surgery patients by plasma proteomics

CQ Liu, YJ Gao, GX Lin, JZ Liang, YF Li… - Journal of Orthopaedic …, 2023 - Springer
Background Due to the poor specificity of D-dimer, more accurate thrombus biomarkers are
clinically needed to improve the diagnostic power of VTE. Methods The plasma samples …

Lower-leg injury and knee arthroscopy have distinct effects on coagulation

CE Touw, B Nemeth, AMR Rondon… - Blood …, 2022 - ashpublications.org
It is unknown how lower-leg injury and knee arthroscopy, both associated with venous
thromboembolism (VTE), affect coagulation. To study the effect of (1) lower-leg trauma and …

Venous thrombosis risk after arthroscopy of the knee: derivation and validation of the L-TRiP (ascopy) score

B Nemeth, RA van Adrichem… - Thrombosis and …, 2018 - thieme-connect.com
Patients at high risk for venous thrombosis (VT) following knee arthroscopy could potentially
benefit from thromboprophylaxis. We explored the predictive values of environmental …

[HTML][HTML] Effect of lower‐leg trauma and knee arthroscopy on procoagulant phospholipid‐dependent activity

CE Touw, B Nemeth, WM Lijfering… - Research and Practice …, 2022 - Elsevier
Background Lower‐leg injury and knee arthroscopy are both associated with venous
thromboembolism (VTE). The mechanism of VTE in both situations is unknown, including the …

[HTML][HTML] The influence of lower-leg injury and knee arthroscopy on natural anticoagulants and fibrinolysis

CE Touw, B Nemeth, RA van Adrichem… - Journal of Thrombosis …, 2023 - Elsevier
Background Patients with lower-leg injuries and those undergoing knee arthroscopy are at
increased risk of developing venous thromboembolism. The mechanism is unknown …

Venous thrombosis following lower-leg cast immobilization and knee arthroscopy: from a population-based approach to individualized therapy

B Nemeth, SC Cannegieter - Thrombosis research, 2019 - Elsevier
Venous thromboembolism (VTE) is a major complication following lower-leg cast
immobilization and knee arthroscopic surgery. In this review, we aimed to give a …

Searching for high-risk venous thromboembolism patients using risk scores: adding to the heap or closing a gap?

IE Albertsen, PB Nielsen - Thrombosis and Haemostasis, 2018 - thieme-connect.com
Venous thromboembolism (VTE) is a serious complication following orthopaedic surgery. 1
However, VTE is largely preventable if patients receive appropriate thromboprophylaxis …

The utility of lower extremity screening duplex for the detection of deep vein thrombosis in trauma

AL Teichman, D Walls, RL Choron, CA Butts… - Journal of Surgical …, 2022 - Elsevier
Background Trauma patients are high-risk for venous thromboembolism (VTE). Lower
extremity screening duplex ultrasonography (LESDUS) is controversial and not …