A Four‐Component Domino Reaction: An Eco‐Compatible and Highly Efficient Construction of 1,8‐Naphthyridine Derivatives, Their In Silico Molecular Docking, Drug …
A multicomponent domino reaction of enaminone, malononitrile, and o‐phthalaldehyde has
been established, providing direct access to novel highly functionalized pentacyclic …
been established, providing direct access to novel highly functionalized pentacyclic …
[PDF][PDF] Synthesis, evaluation and in silico studies of 1, 8-naphthyridine derivatives against antimicrobial activity
S Sachdevaa, S Bhatia, A Mittala… - Journal of Applied …, 2015 - japsonline.com
In present studies a series of novel 1, 8-Naphthyridine derivatives (3a-3f) have been
synthesized using nalidixic acid as a starting material. The structures of the compounds …
synthesized using nalidixic acid as a starting material. The structures of the compounds …
[PDF][PDF] Synthesis, cytotoxicity evaluation, DFT molecular modeling studies and quantitative structure activity relationship of novel 1, 8-naphthyridines
AA Fadda, AM El-Defrawy, SA El-Hadidy - Am J Org Chem, 2012 - researchgate.net
Abstract A series of substituted 1, 8-naphthyridine derivatives were synthesized from 4-oxo-
1, 4-dihydro-1, 8-naphthyridine-3-carbohydrazide (4) as starting material and investigated …
1, 4-dihydro-1, 8-naphthyridine-3-carbohydrazide (4) as starting material and investigated …
Synthesis of naphthalimide derivatives bearing benzothiazole and thiazole moieties: In vitro anticancer and in silico ADMET study
PD JawalePatil, K Bhamidipati, MG Damale… - Journal of Molecular …, 2022 - Elsevier
Herein, we report the synthesis and characterization of 1–16 new naphthalimide derivatives.
These compounds 1–16 were tested for their anticancer activity against cancerous cells …
These compounds 1–16 were tested for their anticancer activity against cancerous cells …
Design, Synthesis, Anticancer Evaluation, and Molecular Docking Studies of Oxazole‐Incorporated Naphthyridine Derivatives
S Rangaswamy, R Sreenivasulu… - Chemistry & …, 2023 - Wiley Online Library
A novel series of oxazole incorporated naphthyridine (21 a–j) derivatives were designed
and, synthesized followed by screening of their anticancer activity profiles against human …
and, synthesized followed by screening of their anticancer activity profiles against human …
[HTML][HTML] Green design, synthesis of novel 2-methoxy-3-aryl-1, 8-naphthyridines and their biological and molecular docking study
An efficient and rapid synthesis of novel substituted 2-methoxy-3-aryl-1, 8-naphthyridines 5
(aj) by the reaction of 2-chloro-3-aryl-1, 8-naphthyridines with sodium methoxide in ethanol …
(aj) by the reaction of 2-chloro-3-aryl-1, 8-naphthyridines with sodium methoxide in ethanol …
Synthesis and anticancer properties of functionalized 1, 6-naphthyridines
M Lavanya, C Lin, J Mao, D Thirumalai… - Topics in Current …, 2021 - Springer
The burgeoning interest in synthesis and biological applications of 1, 6-naphthyridines
reflects the importance of 1, 6-naphthyridines in the synthetic as well as medicinal chemistry …
reflects the importance of 1, 6-naphthyridines in the synthetic as well as medicinal chemistry …
Design, synthesis, molecular docking and in silico ADMET profile of pyrano [2, 3-d] pyrimidine derivatives as antimicrobial and anticancer agents
NEA Abd El-Sattar, K El‐Adl, MA El-Hashash… - Bioorganic …, 2021 - Elsevier
Abstract Pyrano [2, 3-d] pyrimidine derivatives were synthesized by treating cyclic
compounds containing active methylene group with aldehyde and malononitrile in butanol …
compounds containing active methylene group with aldehyde and malononitrile in butanol …
A novel method for the synthesis and characterization of 10-hexyl-3-(1-hexyl-4, 5-diphenyl-1H-imidazol-2-yl)-10H-phenothiazine: DFT computational, in vitro …
JI Ahamed, MF Valan, K Pandurengan… - Research on Chemical …, 2021 - Springer
This study aimed to newly synthesized compound 10-hexyl-3-(1-hexyl-4, 5-diphenyl-1H-
imidazol-2-yl)-10H-phenothiazine (abbreviated as HHDIP) by direct and thermal …
imidazol-2-yl)-10H-phenothiazine (abbreviated as HHDIP) by direct and thermal …
Numerous Heterocyclic Compounds with an Isonicotinic Moiety have Been Studied for Their Synthesis, Antibacterial, Anticancer, Docking Simulation, and DFT …
AM Fahim, EHI Ismael, HEM Tolan - Polycyclic Aromatic …, 2023 - Taylor & Francis
In this elucidation, we focused on the synthesis of isonicotinic heterocyclic molecules
through reaction of isonicotinic acid hydrazide with phthalic anhydride, which produced an …
through reaction of isonicotinic acid hydrazide with phthalic anhydride, which produced an …