Antisense Noncoding RNA in the INK4 Locus (ANRIL) is the prime candidate gene at
Chr9p21, the well-defined genetic risk locus associated with multiple human diseases …

What is known and objective The 3.8‐kb‐long antisense non‐coding RNA at the INK4 locus
(ANRIL) is transcribed from the short arm of human chromosome 9 on P21 and is associated …

Coronary artery disease (CAD) is the leading cause of death worldwide. Long noncoding
RNAs (lncRNAs) are a class of noncoding transcripts of> 200 nucleotides and are …

ANRIL is a newly discovered non-coding RNA lying on the strongest genetic susceptibility
locus for cardiovascular disease (CVD) in the chromosome 9p21 region. Genome-wide …

Accumulating data from genome-wide association studies (GWAS) have provided a
collection of novel candidate genes associated with complex diseases, such as …

This study was designed to investigate whether ANRIL affected the aetiology of coronary
artery disease (CAD) by acting on downstream miR‐181b and NF‐κB signalling. Altogether …

Endothelium inflammation, a key event in vascular pathological process, can lead to
endothelial activation and subsequent vascular disorders. Long non-coding RNA NKILA …

The antisense transcript long non-coding RNA (lncRNA)(antisense non-coding RNA in the
INK4 locus, ANRIL) is an antisense of the cyclin-dependent kinase inhibitor 2B (CDKN2B) …

The chromosome 9p21 (Chr9p21) locus of coronary artery disease has been identified in
the first surge of genome-wide association and is the strongest genetic factor of …

Ever since the first genome-wide association studies (GWAS) on coronary artery disease
(CAD), the Chr9p21 risk locus has emerged as a top signal in GWAS of atherosclerotic …