Photosensitizer encryption with aggregation enhanced singlet oxygen production

C Bloyet, F Sciortino, Y Matsushita… - Journal of the …, 2022 - ACS Publications
Chromophores that generate singlet oxygen (1O2) in water are essential to developing
noninvasive disease treatments using photodynamic therapy (PDT). A facile approach for …

Singlet oxygen-responsive micelles for enhanced photodynamic therapy

X Li, M Gao, K Xin, L Zhang, D Ding, D Kong… - Journal of Controlled …, 2017 - Elsevier
Photodynamic therapy (PDT) efficacy is limited by the very short half-life and limited diffusion
radius of singlet oxygen (1 O 2). We report a 1 O 2-responsive micellar nanoplatform subject …

Highly Efficient Multifunctional Organic Photosensitizer with Aggregation-Induced Emission for In Vivo Bioimaging and Photodynamic Therapy

Y Liao, R Wang, S Wang, Y Xie, H Chen… - … Applied Materials & …, 2021 - ACS Publications
Photosensitizers play a critical role in photodynamic therapy (PDT). Multifunctional organic
nanoparticles (NPs) that possess bright fluorescence in aggregates, high singlet oxygen …

Organically modified silica nanoparticles with intraparticle heavy-atom effect on the encapsulated photosensitizer for enhanced efficacy of photodynamic therapy

S Kim, TY Ohulchanskyy, D Bharali… - The Journal of …, 2009 - ACS Publications
We report a novel nanoassembly formulation for photodynamic therapy, which is composed
of covalently iodine-concentrated organically modified silica (ORMOSIL) nanoparticles …

Controllable singlet oxygen generation in water based on cyclodextrin secondary assembly for targeted photodynamic therapy

X Dai, X Dong, Z Liu, G Liu, Y Liu - Biomacromolecules, 2020 - ACS Publications
The construction of supramolecular assembly whose singlet oxygen (1O2) generation
capability can be controllably regulated in water still remains challenging. Herein, a novel …

Precise molecular engineering of photosensitizers with aggregation‐induced emission over 800 nm for photodynamic therapy

W Wu, D Mao, S Xu… - Advanced Functional …, 2019 - Wiley Online Library
Owing to efficient singlet oxygen (1O2) generation in aggregate state, photosensitizers (PSs)
with aggregation‐induced emission (AIE) have attracted much research interests in …

Photosensitizers dispersed on nanosized triterpenoid matrix with deaggregation-enhanced singlet oxygen production

Z Li, H Xie, H Shi, H Chen, Y Gao - ACS Applied Materials & …, 2023 - ACS Publications
Aggregation-caused quenching (ACQ) effects of photosensitizers severely cut down the
generation of quantum yield of singlet oxygen (1O2) for effective photodynamic therapy …

A nanosystem capable of releasing a photosensitizer bioprecursor under two‐photon irradiation for photodynamic therapy

H Wu, F Zeng, H Zhang, J Xu, J Qiu, S Wu - Advanced Science, 2016 - Wiley Online Library
The applications of photodynamic therapy (PDT) are usually limited by photosensitizers' side
effects and singlet oxygen's short half‐life. Herein, a mitochondria‐targeted nanosystem is …

Inorganic nanomaterials with intrinsic singlet oxygen generation for photodynamic therapy

MR Younis, G He, J Qu, J Lin, P Huang… - Advanced …, 2021 - Wiley Online Library
Inorganic nanomaterials with intrinsic singlet oxygen (1O2) generation capacity, are
emerged yet dynamically developing materials as nano‐photosensitizers (NPSs) for …

A highly efficient and photostable photosensitizer with near‐infrared aggregation‐induced emission for image‐guided photodynamic anticancer therapy

W Wu, D Mao, F Hu, S Xu, C Chen… - Advanced …, 2017 - Wiley Online Library
Photodynamic therapy (PDT), which relies on photosensitizers (PS) and light to generate
reactive oxygen species to kill cancer cells or bacteria, has attracted much attention in recent …