Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence

Y Tan, Z Zhang, C Zheng, KA Wintergerst… - Nature Reviews …, 2020 - nature.com
The pathogenesis and clinical features of diabetic cardiomyopathy have been well-studied
in the past decade, but effective approaches to prevent and treat this disease are limited …

[HTML][HTML] Diabetic cardiomyopathy: current and future therapies. Beyond glycemic control

G Borghetti, D Von Lewinski, DM Eaton… - Frontiers in …, 2018 - frontiersin.org
Diabetes mellitus and the associated complications represent a global burden on human
health and economics. Cardiovascular diseases are the leading cause of death in diabetic …

Diabetic cardiomyopathy: mechanisms and therapeutic targets

PK Battiprolu, TG Gillette, ZV Wang… - Drug Discovery Today …, 2010 - Elsevier
The incidence and prevalence of diabetes mellitus are each increasing rapidly in our
society. The majority of patients with diabetes succumb ultimately to heart disease, much of …

[HTML][HTML] Diabetic cardiomyopathy: a hyperglycaemia-and insulin-resistance-induced heart disease

G Jia, A Whaley-Connell, JR Sowers - Diabetologia, 2018 - Springer
Diabetic cardiomyopathy is characterised in its early stages by diastolic relaxation
abnormalities and later by clinical heart failure in the absence of dyslipidaemia …

Are targeted therapies for diabetic cardiomyopathy on the horizon?

M Tate, DJ Grieve, RH Ritchie - Clinical Science, 2017 - portlandpress.com
Diabetes increases the risk of heart failure approximately 2.5-fold, independent of coronary
artery disease and other comorbidities. This process, termed diabetic cardiomyopathy, is …

Diabetic cardiomyopathy, causes and effects

S Boudina, ED Abel - Reviews in Endocrine and Metabolic Disorders, 2010 - Springer
Diabetes is associated with increased incidence of heart failure even after controlling for
coronary artery disease and hypertension. Thus, as diabetic cardiomyopathy has become …

Diabetic cardiomyopathy-a comprehensive updated review

G Murtaza, HUH Virk, M Khalid, CJ Lavie… - Progress in …, 2019 - Elsevier
Diabetes causes cardiomyopathy and increases the risk of heart failure independent of
hypertension and coronary heart disease. This condition called “Diabetic Cardiomyopathy” …

Diabetic cardiomyopathy: mechanisms, diagnosis and treatment

SA Hayat, B Patel, RS Khattar, RA Malik - Clinical science, 2004 - portlandpress.com
Independent of the severity of coronary artery disease, diabetic patients have an increased
risk of developing heart failure. This clinical entity has been considered to be a distinct …

Diabetic cardiomyopathy: molecular mechanisms, detrimental effects of conventional treatment, and beneficial effects of natural therapy

B Parim, VV Sathibabu Uddandrao, G Saravanan - Heart Failure Reviews, 2019 - Springer
Diabetic complications are among the largely exigent health problems currently.
Cardiovascular complications, including diabetic cardiomyopathy (DCM), account for more …

Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options

A Aneja, WHW Tang, S Bansilal, MJ Garcia… - The American journal of …, 2008 - Elsevier
Diabetic cardiomyopathy is the presence of myocardial dysfunction in the absence of
coronary artery disease and hypertension. Hyperglycemia seems to be central to the …