Neurological disorders such as Alzheimer's disease, stroke, and brain cancers are difficult to
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …

The existence of blood–brain barrier (BBB) hampers the effective treatment of central
nervous system (CNS) diseases. Almost all macromolecular drugs and more than 98% of …

Delivery of therapeutic agents to the central nervous system is a significant challenge,
hindering progress in the treatment of diseases such as glioblastoma. Due to the presence …

A major obstacle facing brain diseases such as Alzheimer's disease, multiple sclerosis,
brain tumors, and strokes is the blood–brain barrier (BBB). The BBB prevents the passage of …

Abstract Treatment of brain‐related diseases is challenging due to the presence of the blood–
brain barrier (BBB), a hurdle that prevents most foreign matter from entering the brain. While …

Noninvasive treatments to treat the brain-related disorders have been paying more
significant attention and it is an emerging topic. However, overcoming the blood brain barrier …

The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …

Neurodegenerative diseases are common, incurable neurological disorders with high
prevalence, and lead to memory, movement, language, and intelligence impairments …

The blood–brain barrier (BBB) is a vital boundary between neural tissue and circulating
blood. The BBB's unique and protective features control brain homeostasis as well as ion …

The delivery of therapeutics to the brain in an efficient, noninvasive manner continues to be
a major unmet need in the field of drug delivery. One significant impediment to brain delivery …