[HTML][HTML] Tanshinone IIA suppresses proliferation and inflammatory cytokine production of synovial fibroblasts from rheumatoid arthritis patients induced by TNF-α and …
H Du, Y Wang, Y Zeng, X Huang, D Liu, L Ye… - Frontiers in …, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease in which
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …
activated RA fibroblast-1ike synoviocytes (RA-FLSs) are one of the main factors responsible …
Tanshinone IIA induces apoptosis in fibroblast-like synoviocytes in rheumatoid arthritis via blockade of the cell cycle in the G2/M phase and a mitochondrial pathway
L Jie, H Du, Q Huang, S Wei, R Huang… - Biological and …, 2014 - jstage.jst.go.jp
Abstract Tanshinone IIA (Tan IIA), a phytochemical derived from the roots of Salvia
miltiorrhiza BUNGE, has been documented with anti-tumor, pro-apoptotic, and anti …
miltiorrhiza BUNGE, has been documented with anti-tumor, pro-apoptotic, and anti …
Tanshinone IIA ameliorates chronic arthritis in mice by modulating neutrophil activities
S Zhang, G Huang, K Yuan, Q Zhu… - Clinical & …, 2017 - academic.oup.com
Rheumatoid arthritis (RA) is a chronic immune inflammatory disease mediated by the influx
of immune cells into the synovial joint space. As Tanshinone IIA (TIIA) has potent anti …
of immune cells into the synovial joint space. As Tanshinone IIA (TIIA) has potent anti …
Tanshinone I inhibits IL-1β-induced apoptosis, inflammation and extracellular matrix degradation in chondrocytes CHON-001 cells and attenuates murine …
X Wang, J Fan, X Ding, Y Sun, Z Cui… - … design, development and …, 2019 - Taylor & Francis
Background: Osteoarthritis (OA) is a prevalent degenerative joint disease, which was
characterized by inflammation and cartilage degradation. Accumulating evidence has …
characterized by inflammation and cartilage degradation. Accumulating evidence has …
Sodium tanshinone IIA sulfonate inhibits proliferation, migration, invasion and inflammation in rheumatoid arthritis fibroblast-like synoviocytes
Z Wang, J Li, J Zhang, X Xie - International Immunopharmacology, 2019 - Elsevier
Our study aimed to determine the effects of sodium tanshinone IIA sulfonate (STS) on
proliferation, migration, invasion, and inflammation in rheumatoid arthritis human fibroblast …
proliferation, migration, invasion, and inflammation in rheumatoid arthritis human fibroblast …
[HTML][HTML] Articular cartilage degradation is prevented by tanshinone IIA through inhibiting apoptosis and the expression of inflammatory cytokines
PT Jia, XL Zhang, HN Zuo, X Lu… - Molecular Medicine …, 2017 - spandidos-publications.com
The present study aimed to investigate the effect of tanshinone IIA on the degradation of
articular cartilage in a rat model of osteoarthritis (OA). The OA rat model was established by …
articular cartilage in a rat model of osteoarthritis (OA). The OA rat model was established by …
[HTML][HTML] Inhibitory effect of tanshinone IIA on inflammatory response in rheumatoid arthritis through regulating β‑arrestin 2
J Tang, S Zhou, F Zhou, X Wen - Experimental and …, 2019 - spandidos-publications.com
The current study aimed to investigate the inhibitory effect of tanshinone IIA (Tan IIA) on the
inflammatory response in patients with rheumatoid arthritis (RA) and explore its mechanism …
inflammatory response in patients with rheumatoid arthritis (RA) and explore its mechanism …
[HTML][HTML] Tomatidine suppresses the destructive behaviors of fibroblast-like synoviocytes and ameliorates type II collagen-induced arthritis in rats
X Yu, J Zhou, F Zhao, X Liu, Y Mao, L Diao… - Frontiers in …, 2021 - frontiersin.org
Fibroblast-like synoviocytes (FLSs) are the prominent non-immune cells in synovium and
play a pivotal role in rheumatoid arthritis (RA) pathogenesis. Searching for natural …
play a pivotal role in rheumatoid arthritis (RA) pathogenesis. Searching for natural …
[HTML][HTML] Alleviation of synovial inflammation of Juanbi-Tang on collagen-induced arthritis and TNF-Tg mice model
T Wang, Q Jia, T Chen, H Yin, X Tian, X Lin… - Frontiers in …, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease that is primarily characterized by
synovial inflammation. In this study, we found that a traditional Chinese decoction, Juanbi …
synovial inflammation. In this study, we found that a traditional Chinese decoction, Juanbi …
Tanshinone IIA promotes the apoptosis of fibroblast-like synoviocytes in rheumatoid arthritis by up-regulating lncRNA GAS5
G Li, Y Liu, F Meng, Z Xia, X Wu, Y Fang… - Bioscience …, 2018 - portlandpress.com
Rheumatoid arthritis (RA) is a common chronic autoimmune joint disease characteristic of
elevated proliferation and infiltration of fibroblast-like synoviocytes (FLS). Here, we aimed to …
elevated proliferation and infiltration of fibroblast-like synoviocytes (FLS). Here, we aimed to …
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