[HTML][HTML] Acute and persistent effects of commonly used antibiotics on the gut microbiome and resistome in healthy adults

WE Anthony, B Wang, KV Sukhum, AW D'Souza… - Cell reports, 2022 - cell.com
Antibiotics are deployed against bacterial pathogens, but their targeting of conserved
microbial processes means they also collaterally perturb the commensal microbiome. To …

[HTML][HTML] Recovery of the gut microbiota after antibiotics depends on host diet, community context, and environmental reservoirs

KM Ng, A Aranda-Díaz, C Tropini, MR Frankel… - Cell host & …, 2019 - cell.com
Antibiotics alter microbiota composition and increase infection susceptibility. However, the
generalizable effects of antibiotics on and the contribution of environmental variables to gut …

[HTML][HTML] Understanding the impact of antibiotic perturbation on the human microbiome

DJ Schwartz, AE Langdon, G Dantas - Genome medicine, 2020 - Springer
The human gut microbiome is a dynamic collection of bacteria, archaea, fungi, and viruses
that performs essential functions for immune development, pathogen colonization …

Antibiotic perturbations to the gut microbiome

SRS Fishbein, B Mahmud, G Dantas - Nature Reviews Microbiology, 2023 - nature.com
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

[HTML][HTML] Antibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

B Seelbinder, J Chen, S Brunke, R Vazquez-Uribe… - Microbiome, 2020 - Springer
Background Antibiotic treatment has a well-established detrimental effect on the gut
bacterial composition, but effects on the fungal community are less clear. Bacteria in the …

[HTML][HTML] Gut microbiota response to antibiotics is personalized and depends on baseline microbiota

A Rashidi, M Ebadi, TU Rehman, H Elhusseini… - Microbiome, 2021 - Springer
Background The magnitude of microbiota perturbations after exposure to antibiotics varies
among individuals. It has been suggested that the composition of pre-treatment microbiota …

The initial state of the human gut microbiome determines its reshaping by antibiotics

F Raymond, AA Ouameur, M Déraspe, N Iqbal… - The ISME …, 2016 - academic.oup.com
Microbiome studies have demonstrated the high inter-individual diversity of the gut
microbiota. However, how the initial composition of the microbiome affects the impact of …

Effects of antibiotic treatment on gut microbiota and how to overcome its negative impacts on human health

CFA Ribeiro, GGOS Silveira, ES Candido… - ACS Infectious …, 2020 - ACS Publications
The need for new antimicrobial therapies is evident, especially to reduce antimicrobial
resistance and minimize deleterious effects on gut microbiota. However, although diverse …

Long-term impacts of antibiotic exposure on the human intestinal microbiota

C Jernberg, S Lofmark, C Edlund… - Microbiology, 2010 - microbiologyresearch.org
Although it is known that antibiotics have short-term impacts on the human microbiome,
recent evidence demonstrates that the impacts of some antibiotics remain for extended …

Antibiotic treatment drives the diversification of the human gut resistome

J Li, EA Rettedal, E van der Helm… - Genomics …, 2019 - academic.oup.com
Despite the documented antibiotic-induced disruption of the gut microbiota, the impact of
antibiotic intake on strain-level dynamics, evolution of resistance genes, and factors …