Extracellular vesicles as delivery systems at nano-/micro-scale

P Fu, J Zhang, H Li, M Mak, W Xu, Z Tao - Advanced drug delivery reviews, 2021 - Elsevier
Extracellular vesicles (EVs) have shown significant promises as nano-/micro-size carriers in
drug delivery and bioimaging. With more characteristics of EVs explored through …

Extracellular vesicle-based therapeutics: preclinical and clinical investigations

NL Klyachko, CJ Arzt, SM Li, OA Gololobova… - Pharmaceutics, 2020 - mdpi.com
Drug nanoformulations hold remarkable promise for the efficient delivery of therapeutics to a
disease site. Unfortunately, artificial nanocarriers, mostly liposomes and polymeric …

Recent advances on extracellular vesicles in therapeutic delivery: Challenges, solutions, and opportunities

M Lu, H Xing, Z Yang, Y Sun, T Yang, X Zhao… - European Journal of …, 2017 - Elsevier
Extracellular vesicles (EVs) are intrinsic mediators of intercellular communication in our
body, allowing functional transfer of biomolecules (lipids, proteins, and nucleic acid) …

Extracellular vesicles as drug delivery systems: lessons from the liposome field

R van der Meel, MHAM Fens, P Vader… - Journal of controlled …, 2014 - Elsevier
Extracellular vesicles (EVs) are membrane-derived particles surrounded by a (phospho)
lipid bilayer that are released by cells in the human body. In addition to direct cell-to-cell …

Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

Emerging prospects of extracellular vesicles for brain disease theranostics

R Wang, X Wang, Y Zhang, H Zhao, J Cui, J Li… - Journal of Controlled …, 2022 - Elsevier
In the past decade, bio-nanoparticles inspired by nature with advantageous properties have
attracted extensive interest for accurate diagnosis and effective treatment. Extracellular …

Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases

D Rufino-Ramos, PR Albuquerque, V Carmona… - Journal of Controlled …, 2017 - Elsevier
Extracellular vesicles (EVs) are cell-derived membrane vesicles virtually secreted by all
cells, including brain cells. EVs are a major term that includes apoptotic bodies …

Advances of engineered extracellular vesicles-based therapeutics strategy

H Komuro, S Aminova, K Lauro… - Science and Technology …, 2022 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous population of lipid bilayer membrane-
bound vesicles which encapsulate bioactive molecules, such as nucleic acids, proteins, and …

[HTML][HTML] Extracellular vesicles as drug delivery systems: Why and how?

OM Elsharkasy, JZ Nordin, DW Hagey… - Advanced drug delivery …, 2020 - Elsevier
Over the past decades, a multitude of synthetic drug delivery systems has been developed
and introduced to the market. However, applications of such systems are limited due to …

Extracellular vesicles–advanced nanocarriers in cancer therapy: progress and achievements

T Huyan, H Li, H Peng, J Chen, R Yang… - International journal …, 2020 - Taylor & Francis
Extracellular vesicles (EVs) are a class of cell-derived, lipid bilayer membrane composed
vesicles, and some of them such as exosomes and ectosomes have been proven, playing …