To investigate at the population level the impact of BRCA1/BRCA2 gene alterations in male
breast cancer, we analyzed a population-based series of 25 male breast cancer cases from …

Purpose: Germline mutations of the BRCA2 gene are involved in the development of a
considerable number of male breast cancer cases. Although phenotypic differences have …

Background Mutations in the BRCA2 gene account for the majority of the families with male
and female breast cancer cases, and a number of BRCA2 mutations have been reported in …

Background Male breast cancer (MBC) is a rare and scarcely investigated disease. The
strongest genetic risk factor for MBC is represented by inherited BRCA2 mutations, whereas …

To determine the contribution of BRCA1 and BRCA2 mutations to the pathogenesis of male
breast cancer in Hungary, the country with the highest male breast cancer mortality rates in …

Background Male breast cancer (MBC) is a rare disease and little is known about its
aetiology. Germ-line mutations of BRCA2 and, at lower frequency, of BRCA1 are implicated …

Background The contribution of BRCA1 and BRCA2 to the incidence of male breast cancer
(MBC) in the United Kingdom is not known, and the importance of these genes in the …

Breast cancer is a rare disease in men. Germ‐line mutations in BRCA2 and androgen
receptor (AR) genes are thought to be responsible for a proportion of male breast cancer …

The etiology and pathogenesis of male breast cancer (MBC) are poorly known. This is due
to the fact that the disease is rare, and large-scale genetic epidemiologic studies have been …

The genetic changes underlying the development and progression of male breast cancer
are poorly understood. Germline BRCA2 mutations account for a significant part of male …