Targeting strategies for superparamagnetic iron oxide nanoparticles in cancer therapy

D Zhi, T Yang, J Yang, S Fu, S Zhang - Acta biomaterialia, 2020 - Elsevier
Among various nanoparticles, superparamagnetic iron oxide nanoparticles (SPIONs) have
been increasingly studied for their excellent superparamagnetism, magnetic heating …

Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy

M Mahmoudi, S Sant, B Wang, S Laurent… - Advanced drug delivery …, 2011 - Elsevier
At present, nanoparticles are used for various biomedical applications where they facilitate
laboratory diagnostics and therapeutics. More specifically for drug delivery purposes, the …

Superparamagnetic iron oxide nanoparticles: magnetic nanoplatforms as drug carriers

null Wahajuddin, S Arora - International journal of nanomedicine, 2012 - Taylor & Francis
A targeted drug delivery system is the need of the hour. Guiding magnetic iron oxide
nanoparticles with the help of an external magnetic field to its target is the principle behind …

Development of superparamagnetic iron oxide nanoparticles (SPIONS) for translation to clinical applications

MM Lin, DK Kim, AJ El Haj… - IEEE transactions on …, 2008 - ieeexplore.ieee.org
Superparamagnetic iron oxide nanoparticles (SPIONs) have attract a great deal of interest in
biomedical research and clinical applications over the past decades. Taking advantage the …

Development and characterization of magnetic iron oxide nanoparticles with a cisplatin-bearing polymer coating for targeted drug delivery

H Unterweger, R Tietze, C Janko, J Zaloga… - International journal …, 2014 - Taylor & Francis
A highly selective and efficient cancer therapy can be achieved using magnetically directed
superparamagnetic iron oxide nanoparticles (SPIONs) bearing a sufficient amount of the …

Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) as platform for the targeted multimodal tumor therapy

C Janko, T Ratschker, K Nguyen, L Zschiesche… - Frontiers in …, 2019 - frontiersin.org
Standard cancer treatments involve surgery, radiotherapy, chemotherapy, and
immunotherapy. In clinical practice, the respective drugs are applied orally or intravenously …

Superparamagnetic iron oxide nanoparticles conjugated with folic acid for dual target-specific drug delivery and MRI in cancer theranostics

Y Huang, K Mao, B Zhang, Y Zhao - Materials Science and Engineering: C, 2017 - Elsevier
Monodispersed SPIONs (superparamagnetic iron oxide nanoparticles) co-coated with PEG
and PEI polymers were prepared by an improved polyol method. To accomplish cancer …

Superparamagnetic iron oxide nanoparticles for delivery of therapeutic agents: opportunities and challenges

S Laurent, AA Saei, S Behzadi… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Bearing in mind that many promising drug candidates have the problem of
reaching their target site, the concept of advanced drug delivery can play a significant …

Nanovectors for anticancer agents based on superparamagnetic iron oxide nanoparticles

L Douziech-Eyrolles, H Marchais, K Hervé… - International journal …, 2007 - Taylor & Francis
During the last decade, the application of nanotechnologies for anticancer drug delivery has
been extensively explored, hoping to improve the efficacy and to reduce side effects of …

Recent advances in superparamagnetic iron oxide nanoparticles (SPIONs) for in vitro and in vivo cancer nanotheranostics

G Kandasamy, D Maity - International journal of pharmaceutics, 2015 - Elsevier
Recently superparamagnetic iron oxide nanoparticles (SPIONs) have been extensively used
in cancer therapy and diagnosis (theranostics) via magnetic targeting, magnetic resonance …