Lung cancer (LC) represents one of the most prevalent health issues globally and is a
leading cause of tumor-related mortality. Despite being one the most attractive compounds …

In this study, we investigated the anti-cancer effects of luteolin, a member of the flavonoid
family, in NCI-H460 human lung carcinoma cells. It was shown that luteolin induces …

Tumor necrosis factor‑related apoptosis-inducing ligand (TRAIL) is well known as a
transmembrane cytokine and has been proposed as one of the most effective anti‑cancer …

Anti‐cancer drugs generally kill cancer cells by apoptosis but fail to do so when they
become resistant and escape apoptosis signals. But these resistant cells can still be killed …

Autophagy has attracted a great deal of interest in tumour therapy research in recent years.
However, the anticancer effect of luteoloside, a naturally occurring flavonoid isolated from …

Introduction: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered
to be an effective apoptosis inducer due to its selectivity for tumor cells. However, many …

The signal transducers and activators of transcription 3 (STAT3) signaling pathway is a
common feature in many solid tumors including non‐small cell lung cancer, whereas current …

Sesquiterpene lactones have been shown to be promising leads for anticancer drug
development. Brevilin A (BLN-A), a sesquiterpene lactone compound of Centipeda minima …

Lambertianic acid (LA) is a biologically active compound from the leaves of Pinus
koraiensis. In the present study, apoptotic mechanisms of LA plus TNF-related apoptosis …

With a high mortality rate, non-small cell lung cancer (NSCLC) is a major challenge for
patients and clinicians. The high cost and side effects of chemo-drugs severely influence …