Lipid raft is an important element for the cellular entry of some viruses, including coronavirus
infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular …

Although several reports suggest that the entry of infectious bronchitis virus (IBV) depends
on lipid rafts and low pH, the endocytic route and intracellular trafficking are unclear. In this …

Lipid rafts are functional membrane microdomains containing sphingolipids, including
gangliosides, and cholesterol. These regions are characterized by highly ordered and tightly …

Lipid rafts have an important property to preferentially concentrate some proteins, while
excluding others. Lipid rafts can also act as functional platforms for multiple signalling and …

Cholesterol and sphingolipid enriched lipid raft micro-domains in the plasma membrane
play an important role in the life-cycle of numerous enveloped viruses. Although human …

Virus entry, assembly, and budding are important processes in the replication cycle of a
virus. Viruses are dependent on host living cells for their replication. Viruses use the …

Coronaviruses are enveloped, single-stranded, positive-sense RNA viruses that can infect
animal and human hosts. The infection induces mild or sometimes severe acute respiratory …

Cholesterol-rich lipid raft microdomains in the plasma membrane are considered to play a
major role in the enveloped virus lifecycle. However, the functional role of cholesterol in …

Coronaviruses are enveloped RNA viruses that have evolved complex relationships with
their host cells, and modulate their lipid composition, lipid synthesis and signalling. Lipid …

Coronavirus M protein is an essential component of virion and plays pivotal roles in virion
assembly, budding and maturation. The M protein is integrated into the viral envelope with …