Differential airway remodeling changes were observed in patients with asthma COPD overlap compared to patients with asthma and COPD alone

S Dey, W Lu, HC Weber, S Young… - … of Physiology-Lung …, 2022 - journals.physiology.org
Management of patients with asthma COPD overlap (ACO) is clinically challenging due to
insufficient evidence of pathological changes in these patients. In this cross-sectional study …

Large airway wall vascularity in patients with Asthma COPD overlap: a bronchoscopy study

S Dey, W Lu, HC Weber, C Chia… - ERJ Open …, 2024 - Eur Respiratory Soc
Asthma COPD overlap (ACO) is a clinical term that describes patients with persistent airflow
limitation, and clinical/physiologic characteristics consistent with both asthma and chronic …

Remodeling in asthma and COPD–differences and similarities

CM Sköld - The clinical respiratory journal, 2010 - Wiley Online Library
Background: Asthma and chronic obstructive pulmonary disease (COPD) are both
inflammatory disorders. Diagnosis of these diseases is based upon limitation of expiratory …

[HTML][HTML] Airway inflammatory changes in the lungs of patients with asthma-COPD overlap (ACO): a bronchoscopy endobronchial biopsy study

S Dey, W Lu, G Haug, C Chia, J Larby, HC Weber… - Respiratory …, 2023 - Springer
Background Although asthma and chronic obstructive pulmonary disease (COPD) are two
distinct chronic airway inflammatory diseases, they often co-exist in a patient and the …

Pathogenesis, clinical features of asthma COPD overlap, and therapeutic modalities

S Dey, MS Eapen, C Chia… - … of Physiology-Lung …, 2022 - journals.physiology.org
Both asthma and COPD are heterogeneous diseases identified by characteristic symptoms
and functional abnormalities, with airway obstruction common in both diseases. Asthma …

[HTML][HTML] Physiological and morphological differences of airways between COPD and asthma–COPD overlap

M Karayama, N Inui, H Yasui, M Kono, H Hozumi… - Scientific reports, 2019 - nature.com
Overlap of asthma and COPD has attracted attention recently. We aimed to clarify
physiological and morphological differences of the airways between COPD and asthma …

Airway remodelling in COPD: It's not asthma!

RL Jones, PB Noble, JG Elliot, AL James - Respirology, 2016 - Wiley Online Library
ABSTRACT COPD is defined as airflow limitation that is not reversed by treatment. In
asthma, airflow limitation is not only reversible, but also inducible. This is called 'airway …

Clinical relevance of airway remodelling in airway diseases

AL James, S Wenzel - European Respiratory Journal, 2007 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD) are characterised by airflow
obstruction, airway remodelling (measurable structural change) and inflammation. The …

Differences in airway structural changes assessed by 3-dimensional computed tomography in asthma and asthma–chronic obstructive pulmonary disease overlap

M Niwa, T Fujisawa, M Karayama, K Furuhashi… - Annals of Allergy …, 2018 - Elsevier
Background Asthma–chronic obstructive pulmonary disease (COPD) overlap (ACO) is a
clinical phenotype sharing features of asthma and COPD. Multidetector row computed …

Asthma-COPD overlap phenotypes and smoking: comparative features of asthma in smoking or non-smoking patients with an incomplete reversibility of airway …

LP Boulet, MÈ Boulay, JL Dérival, J Milot… - COPD: Journal of …, 2018 - Taylor & Francis
The development of COPD features, such as an incomplete reversibility of airway
obstruction (IRAO), in smoking or non-smoking asthmatic patients, a condition often named …