Impact of Chronic Exposure to Endometriosis on Perinatal Outcomes: Establishment of a Mouse Model

M Elsherbini, K Koga, E Maki, K Kumasawa, E Satake… - Biomedicines, 2022 - mdpi.com
The purpose of this study was to establish a new mouse model of endometriosis that mimics
real-world women's health problems, in which women continue to be affected by …

Rodent models of experimental endometriosis: identifying mechanisms of disease and therapeutic targets

KL Bruner-Tran, S Mokshagundam… - Current women's …, 2018 - ingentaconnect.com
Background: Although it has been more than a century since endometriosis was initially
described in the literature, understanding the etiology and natural history of the disease has …

Translational animal models to study endometriosis-associated infertility

R Grümmer - Seminars in reproductive medicine, 2013 - thieme-connect.com
Although there is an apparent association between endometriosis and impaired fertility, the
pathophysiology of the reduced fecundity in women with endometriosis still remains unclear …

Dose-dependent decreased fertility in response to the burden of endometriosis in a murine model

ACJS Rosa-e-Silva, JC Rosa-e-Silva… - Reproductive …, 2019 - journals.sagepub.com
Endometriosis is a gynecological disease caused by the growth of endometrial cells outside
the uterus leading to inflammation, pelvic pain, and infertility. The relationship between the …

Lesion development is modulated by the natural estrous cycle and mouse strain in a minimally invasive model of endometriosis

KN Dodds, EAH Beckett, SF Evans… - Biology of …, 2017 - academic.oup.com
Many rodent models of endometriosis are invasive, involving surgery to implant donor
endometrial tissue into recipient animals. Moreover, few studies have compared and …

Endometriosis research: animal models for the study of a complex disease

I Tirado-González, G Barrientos, N Tariverdian… - Journal of reproductive …, 2010 - Elsevier
Endometriosis is a common gynaecological disease that is characterized and defined as the
presence of endometrial tissue outside the uterus, causing painful periods and subfertility in …

Animal studies in endometriosis: a review

L Story, S Kennedy - ILAR journal, 2004 - academic.oup.com
Endometriosis is a common women's health problem that is characterized by the presence
of tissue resembling endometrium outside the uterus. The condition causes painful periods …

Primate model research for endometriosis

A Yamanaka, F Kimura, A Takebayashi… - The Tohoku journal of …, 2012 - jstage.jst.go.jp
Endometriosis is defined as the existence of endometrial tissue outside the uterine cavity,
and it includes a chronic, inflammatory reaction associated with female infertility and pelvic …

Interplay between endometriosis and pregnancy in a mouse model

MA Bilotas, CN Olivares, AG Ricci, JI Baston… - PloS one, 2015 - journals.plos.org
Objectives To evaluate the effect of endometriosis on fertility and the levels of the IL-2 and
IFN-γ in the peritoneal fluid in a mouse model; to evaluate the effect of pregnancy on …

[HTML][HTML] Animal models for research on endometriosis

F Taniguchi, H Wibisono, YM Khine… - Frontiers in Bioscience …, 2020 - imrpress.com
Endometriosis results from the aberrant growth of endometrium outside the inner lining of
the uterine cavity. Similar to humans, the primates also menstruate and hence, the primate …