Growth hormone action in somatostatin neurons regulates anxiety and fear memory
WO Dos Santos, VAL Juliano, FM Chaves… - Journal of …, 2023 - Soc Neuroscience
Dysfunctions in growth hormone (GH) secretion increase the prevalence of anxiety and
other neuropsychiatric diseases. GH receptor (GHR) signaling in the amygdala has been …
other neuropsychiatric diseases. GH receptor (GHR) signaling in the amygdala has been …
Effects of disrupted ghrelin receptor function on fear processing, anxiety and saccharin preference in mice
A Pierre, Y Regin, A Van Schuerbeek, EM Fritz… - …, 2019 - Elsevier
Background Obesity is a risk factor for stress-related mental disorders such as post-traumatic
stress disorder. The underlying mechanism through which obesity affects mental health …
stress disorder. The underlying mechanism through which obesity affects mental health …
Desacyl ghrelin decreases anxiety-like behavior in male mice
P Mahbod, EP Smith, ME Fitzgerald, RL Morano… - …, 2018 - academic.oup.com
Ghrelin is a 28–amino acid polypeptide that regulates feeding, glucose metabolism, and
emotionality (stress, anxiety, and depression). Plasma ghrelin circulates as desacyl ghrelin …
emotionality (stress, anxiety, and depression). Plasma ghrelin circulates as desacyl ghrelin …
A ghrelin–growth hormone axis drives stress-induced vulnerability to enhanced fear
RM Meyer, A Burgos-Robles, E Liu, SS Correia… - Molecular …, 2014 - nature.com
Hormones in the hypothalamus–pituitary–adrenal (HPA) axis mediate many of the bodily
responses to stressors, yet there is no clear relationship between the levels of these …
responses to stressors, yet there is no clear relationship between the levels of these …
Growth hormone biases amygdala network activation after fear learning
Prolonged stress exposure is a risk factor for developing posttraumatic stress disorder, a
disorder characterized by the 'over-encoding'of a traumatic experience. A potential …
disorder characterized by the 'over-encoding'of a traumatic experience. A potential …
Ghrelin regulates the hypothalamic-pituitary-adrenal axis and restricts anxiety after acute stress
SJ Spencer, L Xu, MA Clarke, M Lemus… - Biological …, 2012 - Elsevier
BACKGROUND: Ghrelin plays important roles in glucose metabolism, appetite, and body
weight regulation, and recent evidence suggests ghrelin prevents excessive anxiety under …
weight regulation, and recent evidence suggests ghrelin prevents excessive anxiety under …
The protective effects of Ghrelin/GHSR on hippocampal neurogenesis in CUMS mice
Ghrelin is an orexigenic hormone that also plays an important role in mood disorders. Our
previous studies demonstrated that ghrelin administration could protect against depression …
previous studies demonstrated that ghrelin administration could protect against depression …
GHS-R1a deficiency alleviates depression-related behaviors after chronic social defeat stress
L Guo, M Niu, J Yang, L Li, S Liu, Y Sun… - Frontiers in …, 2019 - frontiersin.org
Ghrelin is an important orexigenic hormone that regulates feeding, metabolism and glucose
homeostasis in human and rodents. Ghrelin functions by binding to its receptor, the growth …
homeostasis in human and rodents. Ghrelin functions by binding to its receptor, the growth …
Acute but not chronic calorie restriction defends against stress-related anxiety and despair in a GHS-R1a-dependent manner
Y Lu, M Niu, X Qiu, H Cao, B Xing, Y Sun, Z Zhou… - Neuroscience, 2019 - Elsevier
Ghrelin is an important orexigenic brain-gut hormone that regulates feeding, metabolism
and glucose homeostasis in human and rodents at multiple levels. Ghrelin functions by …
and glucose homeostasis in human and rodents at multiple levels. Ghrelin functions by …
Anxiolytic-like effects of increased ghrelin receptor signaling in the amygdala
M Jensen, C Ratner, O Rudenko… - International Journal …, 2016 - academic.oup.com
Background: Besides the well-known effects of ghrelin on adiposity and food intake
regulation, the ghrelin system has been shown to regulate aspects of behavior including …
regulation, the ghrelin system has been shown to regulate aspects of behavior including …