The interplay between gut microbiota and the brain-gut axis in Parkinson's disease treatment

X Jia, Q Wang, M Liu, J Ding - Frontiers in Neurology, 2024 - frontiersin.org
This study delves into the pivotal role of the gut microbiota and the brain-gut axis in
Parkinson's Disease (PD), a neurodegenerative disorder with significant motor and non …

Brain-gut-microbiota axis in Parkinson's disease: A historical review and future perspective

S Dong, M Sun, C He, H Cheng - Brain Research Bulletin, 2022 - Elsevier
Parkinson's disease (PD) is the second most common degenerative disease of the central
nervous system (CNS) after Alzheimer's disease. In addition to the typical motor symptoms …

The gut and Parkinson's disease—a bidirectional pathway

SF Santos, HL De Oliveira, ES Yamada… - Frontiers in …, 2019 - frontiersin.org
Humans evolved a symbiotic relationship with their gut microbiome, a complex microbial
community composed of bacteria, archaea, protists, and viruses, including bacteriophages …

Unravelling the role of gut microbiota in Parkinson's disease progression: Pathogenic and therapeutic implications

L Rani, AC Mondal - Neuroscience Research, 2021 - Elsevier
In recent years, researchers have shown interest in bi-directional interaction between the
brain and gut, called “gut-brain axis”. Emerging pieces of evidence indicate that …

The interplay between gut microbiota and Parkinson's disease: Implications on diagnosis and treatment

A Varesi, LIM Campagnoli, F Fahmideh… - International journal of …, 2022 - mdpi.com
The bidirectional interaction between the gut microbiota (GM) and the Central Nervous
System, the so-called gut microbiota brain axis (GMBA), deeply affects brain function and …

Are we what we eat? impact of diet on the gut–brain axis in Parkinson's disease

M Alfonsetti, V Castelli, M d'Angelo - Nutrients, 2022 - mdpi.com
Parkinson's disease is characterized by motor and non-motor symptoms, such as defects in
the gut function, which may occur before the motor symptoms. To date, there are therapies …

Gut Microbes in Parkinson's Disease: Opportunities for Microbial-Based Therapies

A Markidi, JD Elford, C Berkers, AD Kraneveld… - The gut-brain Axis, 2024 - Elsevier
Parkinson's disease is characterized by motor impairments due to the progressive
degeneration of dopaminergic neurons in the substantia nigra of the midbrain, but …

Microbiome-Based Therapies in Parkinson's Disease: Can Tuning the Microbiota Become a Viable Therapeutic Strategy?

AY Onaolapo, FO Ojo, AT Olofinnade… - CNS & Neurological …, 2023 - ingentaconnect.com
Progressive neurodegenerative disorders such as Parkinson's disease (PD) have continued
to baffle medical science, despite strides in the understanding of their pathology. The …

The role of the microbiota-gut-brain axis and intestinal microbiome dysregulation in Parkinson's disease

Q Li, L Meng, L Chen, X Shi, L Tu, Q Zhou, J Yu… - Frontiers in …, 2023 - frontiersin.org
Parkinson's disease (PD) is a complex progressive neurodegenerative disease associated
with aging. Its main pathological feature is the degeneration and loss of dopaminergic …

What is our understanding of the influence of gut microbiota on the pathophysiology of Parkinson's disease?

AE Hill, R Wade-Martins, PWJ Burnet - Frontiers in Neuroscience, 2021 - frontiersin.org
Microbiota have increasingly become implicated in predisposition to human diseases,
including neurodegenerative disorders such as Parkinson's disease (PD). Traditionally, a …